Results 191 to 200 of about 72,847 (330)

Single‐Nucleus RNA Sequencing Reveals Mid‐Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong   +19 more
wiley   +1 more source

DISC1 Regulates Neurotrophin-Induced Axon Elongation via Interaction with Grb2 [PDF]

open access: bronze, 2007
Tomoyasu Shinoda   +7 more
openalex   +1 more source

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou   +14 more
wiley   +1 more source

Downregulation of Voltage-gated Potassium Channel α Gene Expression by Axotomy and Neurotrophins in Rat Dorsal Root Ganglia

open access: hybrid, 2003
So Yun Park   +5 more
openalex   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi   +14 more
wiley   +1 more source

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