Results 121 to 130 of about 26,439 (246)

Neurotrophins: neural antiapoptotic molecules with neurite growth-promoting properties

, 1995
Neurotrophins are a family of small proteins that bind to and activate the members of receptor protein tyrosine kinase family. They also bind the low-affinity neurotrophin receptor (p75).
Arumäe, Urmas; University of Helsinki
core   +1 more source

Exosomal PSMD1 Derived From Dental Pulp Mesenchymal Stem Cells Promotes Microglial M2 Polarization to Alleviate Spinal Cord Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
DPMSCs‐derived exosomal PSMD1 stimulates M2 polarization through the JAK2/STAT3 pathway. DPMSCs‐derived exosomal PSMD1 indirectly acts on NE‐4C cells. DPMSCs‐derived exosomal PSMD1 ameliorates SCI in a mouse model. ABSTRACT Background Exosomes derived from mesenchymal stem cells (MSCs) and their cargo contribute to the protective properties of MSCs in ...
Xiaohui Xing, Yuan Hao, Guanghui Zhang, Xiaoyang Xing, Hongfei Jia, Chenlong Liu, Xin Wang, Tao Li, Xueyuan Li, Yilei Xiao   +9 more
wiley   +1 more source

Effects of Neurotrophins on Cortical Plasticity: Same or Different?

, 2000
Neurotrophins are important regulators of visual cortical plasticity. It is still unclear, however, whether they play similar or different roles and which are their effects on the electrical activity of cortical neuronsin vivo.
Tommaso Pizzorusso, Lamberto Maffei, Nicoletta Berardi, Claudia Lodovichi   +3 more
core   +1 more source

Touch Restriction Versus Free‐Play Small‐Sided Games in Soccer: Acute Effects on Serum BDNF, Executive Function, and Technical Actions

European Journal of Sport Science, Volume 26, Issue 9, September 2026.
ABSTRACT This study aimed to compare the acute effects of two 4v4 small‐sided game (SSG) formats, touch‐restricted SSG (SSGt) and free‐play SSG (SSGf), on serum brain‐derived neurotrophic factor (BDNF) levels, cognitive performance, and technical actions in young male soccer players. Thirty‐two young male soccer players completed two 4v4 SSG conditions
Yakup Zühtü Birinci, Serkan Pancar, Yusuf Soylu, Emre Sarandöl, Hasan Şimşek, Şenay Şahin, Michael C. Rumpf   +6 more
wiley   +1 more source

Dose-dependent effects of testosterone on proteins related to nitric oxide signaling pathway and trophic factors in the spinal cord of adolescent trained rats

Frontiers in Sports and Active Living
IntroductionEndurance training plays an important role in, for example, triathlon, marathon, or road cycling and in combination with strength training.
Katarzyna Nierwińska, Katarzyna Nierwińska, Konstancja Grabowska, Małgorzata Chalimoniuk, Sławomir Jagsz, Józef Langfort, Andrzej Małecki, Marta Nowacka-Chmielewska   +7 more
doaj   +1 more source

Inhibition of Tropomyosin Receptor Kinase B Signaling Alters Hepatic Mitochondrial Enzyme Activity and Oxidative Stress in Mice With Sucrose‐Induced Insulin Resistance

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Suppression of BDNF‐TrkB signaling has shown a protective trend on hepatic oxidative stress by reducing sucrose‐induced lipid peroxidation. BDNF–TrkB signaling pathway plays a peripheral role in regulating mitochondrial enzyme capacity and redox balance in the liver.
Akın Bodur, Hüseyin Çınar Zihni, Katip Korkmaz, Solmaz Bodur, Ahmet Alver   +4 more
wiley   +1 more source

Specificity of neurotrophins in the nervous system : a genetic approach to determine receptor engagement by neurotrophins

, 2004
The classical neurotrophic factor hypothesis describes the neurotrophins as retrograde signalling factors supporting the survival of postmitotic neurons during the development.
Karin Agerman (9730262)
core   +1 more source

Neurotrophins and Proneurotrophins as Biomarkers for Overactive Bladder Syndrome in Aging Females

Metabolites
Background/Objectives: Overactive bladder (OAB), common in elderly women, involves urgency, frequency, and nocturia, with complex phenotypes. The use of neurotrophins as non-invasive urinary biomarkers has been previously explored.
Claudia Covarrubias, Philippe G. Cammisotto, Lysanne Campeau   +2 more
doaj   +1 more source

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

JOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai   +5 more
wiley   +1 more source

Endurance training mitigates obesity-induced hippocampal impairment by enhancing neurotrophin signalling, synaptic plasticity, and cellular responses in a female rat model

IBRO Neuroscience Reports
Obesity-related health issues, including cognitive decline linked to hippocampal neurogenesis and neuroplasticity, are gaining more attention as obesity rates rise worldwide. Physical activity is recognized as a potent stimulator of neurotrophic factors.
Tomáš Kuruc, Karolína Kuchárová, Alexandra Kisucká, Mária Ileninová, Lenka Ihnátová, Katarína Kiss Bimbová, Martina Magurová, Ján Gálik, Nadežda Lukáčová   +8 more
doaj   +1 more source