Results 101 to 110 of about 26,439 (246)
Neurotrophins promote maturation of developing neuromuscular synapses
, 1995 Although the effects of neurotrophins on survival and differentiation of various neuronal populations have been well studied, little is known about their role in synaptic development and function.
B Lu, T Wang, K Xie
core +1 more source
Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring
Experimental Physiology, EarlyView.Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas +2 more
wiley +1 more source
Neurotrophins induce fission of mitochondria along embryonic sensory axons
eLife, 2019 Neurotrophins are growth factors that have a multitude of roles in the nervous system. We report that neurotrophins induce the fission of mitochondria along embryonic chick sensory axons driven by combined PI3K and Mek-Erk signaling. Following an initial
Lorena Armijo-Weingart +5 more
doaj +1 more source
Cortical development: With an eye on neurotrophins [PDF]
, 1996 Recent observations suggest that neurotrophins are involved in activity-dependent plasticity of the developing cerebral cortex.
Ghosh, Anirvan
core +1 more source
Experimental Physiology, EarlyView.Abstract The association between higher levels of physical activity and lower cancer risk and mortality is well established. However, a causal link is yet to be proven. Recent studies showed a decrease in the proliferation rates of cultured human cancer cells when the human serum used to stimulate them was conditioned by acute exercise. Here, we tested
Carlos M. Soares +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova +10 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
BiomedicinesAcute brain injuries (ABIs) pose a substantial global burden, demanding effective prognostic indicators for outcomes. This study explores the potential of urinary p75 neurotrophin receptor (p75NTR) concentration as a prognostic biomarker, particularly in
Santtu Hellström +20 more
doaj +1 more source