Results 211 to 220 of about 47,357 (330)

Targeted Delivery of Microneurotrophin BNN27 via Biomaterial Grafts Protects Retinal Ganglion Cells After Optic Nerve Injury

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 1, January 2026.
ABSTRACT Emerging neurotrophin treatments for optic nerve injury (ONI) aim to prevent the loss of retinal ganglion cells (RGCs) and enhance axonal regeneration. Microneurotrophins (MNTs), small‐molecule mimetics of neurotrophins, have shown neuroprotective effects in various animal models of neurodegeneration, yet MNT effects on ONI remain unknown ...
K. Georgelou   +13 more
wiley   +1 more source

Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity

open access: yesLifestyle Medicine, Volume 7, Issue 1, January 2026.
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien   +4 more
wiley   +1 more source

Therapeutic Effect of Alpha Linolenic Acid on Cutaneous Wound Healing in Hyperglycemic Mice: Involvement of Neurotrophins. [PDF]

open access: yesPharmaceutics
Prado TPD   +9 more
europepmc   +1 more source

The Selective Bromodomain and Extra‐Terminal Domain (BET) Inhibitor RVX‐208 Reduces Cocaine‐Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens

open access: yesAddiction Biology, Volume 31, Issue 1, January 2026.
Rats treated with the domain‐selective BET inhibitor RVX‐208 during a 2‐week forced abstinence period exhibited a reduction in cocaine‐seeking behaviour but not sucrose seeking or open field behaviour. This treatment effect was associated with proteomic changes in pathways relevant to dopaminergic and glutamatergic signalling in the nucleus accumbens ...
Tyler J. Sacko   +3 more
wiley   +1 more source

Computationally Probing the Role of Time‐Limited Neuronal Plasticity in Early Visual Development

open access: yesDevelopmental Science, Volume 29, Issue 1, January 2026.
ABSTRACT In the first months or years of life, newborns learn to perceive their environment at a remarkable pace. This capacity is often attributed to heightened neuronal plasticity that diminishes over time. While this decline in plasticity could be seen as constituting a mere biological constraint, we ask whether it might, in fact, serve an adaptive ...
Marin Vogelsang   +2 more
wiley   +1 more source

Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal   +3 more
wiley   +1 more source

Effects of Stress and Allopregnanolone on the Expression of Neurotrophins and TrkB Receptor in the Sheep Hippocampus. [PDF]

open access: yesInt J Mol Sci
Misztal T   +6 more
europepmc   +1 more source

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