Results 21 to 30 of about 26,439 (246)
Angiogenesis in Gynecological Cancers: Role of Neurotrophins
Frontiers in Oncology, 2019 Angiogenesis, or generation of new blood vessels from other pre-existing, is a key process to maintain the supply of nutrients and oxygen in tissues. Unfortunately, this process is exacerbated in pathologies such as retinopathies and cancers with high ...
Maritza P. Garrido +6 more
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European Journal of Histochemistry, 2009 Nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) and are members of the neurotrophin family, a family of neurotrophic factors that also includes neurotrophin (NT) 3 and NT4/5.
C Squillacioti +3 more
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Current Allergy and Asthma Reports, 2018 Asthma is a chronic airway disease that affects more than 300 million people worldwide. Current treatment focuses on symptomatic relief by temporally dampening inflammation and relaxing the airway. Novel combative strategies against asthma and hopefully a cure are yet to be developed.
Juliana, Barrios, Xingbin, Ai
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Frontiers in Pharmacology, 2022 Agathisflavone is a flavonoid with anti-neuroinflammatory and myelinogenic properties, being also capable to induce neurogenesis. This study evaluated the therapeutic effects of agathisflavone—both as a pharmacological therapy administered in vivo and as
Ravena P. do Nascimento +16 more
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Frontiers in Molecular Neuroscience, 2017 Some therapeutic side-effects result from simultaneous activation of homolog receptors by the same ligand. Tropomyosin receptor kinases (TrkA, TrkB and TrkC) play a major role in the development and biology of neurons through neurotrophin signaling.
Yazan Haddad +5 more
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Activation of Trk neurotrophin receptors in the absence of neurotrophins [PDF]
Proceedings of the National Academy of Sciences, 2001 Neurotrophins regulate neuronal cell survival and synaptic plasticity through activation of Trk receptor tyrosine kinases. Binding of neurotrophins to Trk receptors results in receptor autophosphorylation and downstream phosphorylation cascades.
F S, Lee, M V, Chao
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Influence of Quadrato Motor Training on Salivary proNGF and proBDNF
Frontiers in Neuroscience, 2019 Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).
Micaela Caserta +4 more
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A Single Aplysia Neurotrophin Mediates Synaptic Facilitation via Differentially Processed Isoforms
Cell Reports, 2013 Neurotrophins control the development and adult plasticity of the vertebrate nervous system. Failure to identify invertebrate neurotrophin orthologs, however, has precluded studies in invertebrate models, limiting our understanding of fundamental aspects
Stefan R. Kassabov +5 more
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Nerve Growth Factor and Autoimmune Diseases
Current Issues in Molecular Biology, 2023 NGF plays a crucial immunomodulatory role and increased levels are found in numerous tissues during autoimmune states. NGF directly modulates innate and adaptive immune responses of B and T cells and causes the release of neuropeptides and ...
Sergio Terracina +10 more
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Mice with altered BDNF signaling as models for mood disorders and antidepressant effects
Frontiers in Behavioral Neuroscience, 2014 Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase TrkB support neuronal survival during development and promote connectivity and plasticity in the adult brain.
Jesse Saku Olavi Lindholm +1 more
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