Results 41 to 50 of about 40,543 (253)

Biomimetic Approaches for Separated Regeneration of Sensory and Motor Fibers in Amputee People: Necessary Conditions for Functional Integration of Sensory–Motor Prostheses With the Peripheral Nerves

Frontiers in Bioengineering and Biotechnology, 2020
The regenerative capacity of the peripheral nervous system after an injury is limited, and a complete function is not recovered, mainly due to the loss of nerve tissue after the injury that causes a separation between the nerve ends and to the ...
Atocha Guedan-Duran, Atocha Guedan-Duran, Atocha Guedan-Duran, Nahla Jemni-Damer, Nahla Jemni-Damer, Irune Orueta-Zenarruzabeitia, Irune Orueta-Zenarruzabeitia, Gustavo Víctor Guinea, Gustavo Víctor Guinea, Gustavo Víctor Guinea, Gustavo Víctor Guinea, José Perez-Rigueiro, José Perez-Rigueiro, José Perez-Rigueiro, José Perez-Rigueiro, Daniel Gonzalez-Nieto, Daniel Gonzalez-Nieto, Daniel Gonzalez-Nieto, Fivos Panetsos, Fivos Panetsos, Fivos Panetsos   +20 more
doaj   +1 more source

Expression of Neurotrophins and Their Receptors Tropomyosin-related kinases (Trk) under Tension-stress during Distraction Osteogenesis [PDF]

, 2006
The localization and expression of neurotrophins and their receptors during distraction osteogenesis was investigated in 72 male rat femurs (11 weeks old) to further clarify the concurrence of cellular and molecular events of new bone formation.
Aiga, Ayako, Asaumi, Koji, Kadota, Hiroaki, Lee, You Jin, Mitani, Shigeru, Ozaki, Toshifumi, Takigawa, Masaharu   +6 more
core   +1 more source

The Effects of Nordic Walking With Poles With an Integrated Resistance Shock Absorber on Cognitive Abilities and Cardiopulmonary Efficiency in Postmenopausal Women

Frontiers in Aging Neuroscience, 2020
Late adulthood is associated with atrophy of brain areas, which contribute to cognitive deterioration and increase the risk of depression. On the other hand, aerobic exercise can improve learning and memory function, ameliorate mood, and prevent ...
Katarzyna Domaszewska, Magdalena Koper, Krystian Wochna, Urszula Czerniak, Katarzyna Marciniak, Maciej Wilski, Dorota Bukowska   +6 more
doaj   +1 more source

Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]

, 2016
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela, Giarnieri, Enrico, Giovagnoli, Maria Rosaria, Mancini, Rita, Mariotta, Salvatore, Ricci, Alberto   +5 more
core   +1 more source

miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity [PDF]

, 2013
miR-132 and miR-212 are two closely related miRNAs encoded in the same intron of a small non-coding gene, which have been suggested to play roles in both immune and neuronal function.
A Ucar, A Ucar, AD Wingate, Andrew Macdonald, AS Nudelman, BG Frenguelli, Bruno G. Frenguelli, BW Luikart, C Deplagne, CE Monk, Colin McKenzie, D Edbauer, D Lagos, G Neves, GA Wayman, GR Wiggin, Gyorgy Hutvagner, HI Im, HK Lee, HY Cheng, I Shaked, J Darragh, J Remenyi, J. Simon C. Arthur, JA Hollander, JC Strum, JS Arthur, JS Arthur, Judit Remenyi, K Wibrand, KD Taganov, KF Hansen, LA O’Neill, M Pathania, ME Klein, Mirjam W. M. van den Bosch, MR Fabian, N Mellios, N Vo, Oleg Palygin, P Tognini, R Zaragoza, Rajen B. Mistry, S Anand, S Impey, SA Correa, ST Magill, Thomas Preiss, TJ Lambert, V Molnar, VA Beardmore, VM Ho, VN Kim, WW Anderson, Y Pankratov, YM Clovis, Yuriy Pankratov, YV Pankratov   +57 more
core   +7 more sources

Long-Term Consequences of Developmental Alcohol Exposure on Brain Structure and Function: Therapeutic Benefits of Physical Activity

Brain Sciences, 2012
Developmental alcohol exposure both early in life and during adolescence can have a devastating impact on normal brain structure and functioning, leading to behavioral and cognitive impairments that persist throughout the lifespan.
Gillian F. Hamilton, Anna Y. Klintsova, Karen E. Boschen   +2 more
doaj   +1 more source

Perivascular Innervation in the Nasal Mucosa and Clinical Findings in Patients with Allergic Rhinitis and Idiopathic Rhinitis

International Archives of Otorhinolaryngology, 2023
Introduction The nonspecific hyperreactivity of rhinitis has been attributed to neurotrophins activating sensory nerves and inflammatory cells.
Thiago Carvalho, João Ferreira de Mello Jr, Elia Tamaso Espin Garcia Caldini, Daniel Calduro Salgado, Nicole Mary Garcia de Carvalho, Nilsa Regina Damaceno-Rodrigues, Richard Louis Voegels   +6 more
doaj   +1 more source

Involvement of ras p2I in Neurotrophin-induced Response of Sensory, but Not Sympathetic Neurons [PDF]

, 1993
Little is known about the signal transduction mechanisms involved in the response to neurotrophins and other neurotrophic factors in neurons, beyond the activation of the tyrosine kinase activity of the neurotrophin receptors belonging to the trk family.
Barde, Y. A., Borasio, Gian Domenico, Heumann, R., Markus, A., Wittinghofer, A.   +4 more
core   +3 more sources

The Neurotrophin System in the Postnatal Brain—An Introduction

Biology
Neurotrophins can bind to and signal through specific receptors that belong to the class of the Trk family of tyrosine protein kinase receptors. In addition, they can bind and signal through a low-affinity receptor, termed p75NTR.
Oliver von Bohlen und Halbach, Monique Klausch   +1 more
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source