Results 71 to 80 of about 44,486 (289)

Flexible Transmitter Network [PDF]

arXiv, 2020
Current neural networks are mostly built upon the MP model, which usually formulates the neuron as executing an activation function on the real-valued weighted aggregation of signals received from other neurons. In this paper, we propose the Flexible Transmitter (FT) model, a novel bio-plausible neuron model with flexible synaptic plasticity.
arxiv  

The Effects of Nordic Walking With Poles With an Integrated Resistance Shock Absorber on Cognitive Abilities and Cardiopulmonary Efficiency in Postmenopausal Women

Frontiers in Aging Neuroscience, 2020
Late adulthood is associated with atrophy of brain areas, which contribute to cognitive deterioration and increase the risk of depression. On the other hand, aerobic exercise can improve learning and memory function, ameliorate mood, and prevent ...
Katarzyna Domaszewska, Magdalena Koper, Krystian Wochna, Urszula Czerniak, Katarzyna Marciniak, Maciej Wilski, Dorota Bukowska   +6 more
doaj   +1 more source

Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]

, 2017
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo, Altissimi, Giancarlo, Artico, Marco, Bardella, Lia, Giangaspero, Felice, Minni, Antonio, Parnigotto, Pier Paolo, Pastore, Francesco Saverio, Spoletini, Marialuisa, Taurone, Samanta, Tombolini, Mario, Wierzbicki, Venceslao   +11 more
core   +1 more source

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

CD271 downregulation promotes melanoma progression and invasion in 3-dimensional models and in zebrafish [PDF]

, 2016
CD271 is a neurotrophin receptor variably expressed in melanoma. While contradictory data are reported on its role as a marker of tumor initiating cells, little is known on its function in tumor progression.
Grisendi, Giulia, Lotti, Roberta, Marconi, Alessandra, Palazzo, Elisabetta, Pincelli, Carlo, Quadri, Marika, Saltari, Annalisa, Tiso, Natascia, Truzzi, Francesca   +8 more
core   +1 more source

Balancing neurotrophin pathway and sortilin function: its role in human disease [PDF]

, 2021
Neurotensin receptor-3 or sortilin is a vacuolar protein sorting 10 protein domain (Vps10p) has been firstly discovered in the human brain, it acts as receptor or co-receptor of the cell and traffics different proteins within the cell.
Acha-Sagredo, A., Acha-Sagredo, A., Al-Yozbaki, M., Al-Yozbaki, M., George, A., George, A., Liloglou, T., Liloglou, T., Wilson, C.M., Wilson, C.M.   +9 more
core   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

Advanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Creating well-being: Increased creativity and proNGF decrease following Quadrato Motor Training [PDF]

, 2015
Mind-body practices (MBP) are known to induce electrophysiological and morphological changes, whereas reports related to changes of neurotrophins are surprisingly scarce.
Caterina Pesce, Loredana Verdone, Micaela Caserta, Nicoletta Tocci, Tal Ben Soussan, VENDITTI, Sabrina Donatella Sonia   +5 more
core   +4 more sources

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Neurotrophins and neural stem cells in posttraumatic brain injury repair

Animal Models and Experimental Medicine
Traumatic brain injury (TBI) is the main cause of disability, mental health disorder, and even death, with its incidence and social costs rising steadily.
Wenwen Guo, Ke Liu, Yinghua Wang, Xu Ge, Yifan Ma, Jing Qin, Caiqin Zhang, Ya Zhao, Changhong Shi   +8 more
doaj   +1 more source