Results 111 to 120 of about 14,410 (259)
NEUROVASCULAR COUPLING DURING AGEING AND INMIGRANEURS
A noninvasive assessment of neurovascular coupling using visually evoked cerebral bloodflow velocity responses (VEFR) and visual evoked potentials (VEP), during normal ageingand in migraneurs, would be of great importance for interpretation of functional
Marjan Zaletel
doaj
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik +5 more
wiley +1 more source
Analysis of neurovascular coupling in migraneours
Background: According to recent data it is not clear whether neurovascular coupling is disturbed in migraneours during headache free period. The aim of our study was to establish whether the relationship between visually evoked cerebral blood flow ...
Marjan Zaletel
doaj
Mechanisms to modulate cerebrovascular tone are numerous, interconnected, and spatially dependent, increasing the complexity of experimental study design, interpretation of action-effect pathways, and mechanistic modelling. This difficulty is exacerbated
Sergio Dempsey +3 more
doaj +1 more source
Abstract Background Emerging evidence implicates neuroinflammation in progressive supranuclear palsy (PSP) pathophysiology, with elevated cyto‐chemokines suggesting natural killer (NK) cell involvement. Methods We characterized peripheral NK in PSP (N = 11) versus Parkinson's disease (PD, N = 10) and healthy controls (HC, N = 8) at both ...
Marina Picillo +11 more
wiley +1 more source
Macroscale Gradient‐Informed Neural Oscillation Topography in Parkinson's Disease
Abstract Background Parkinson's disease (PD) is characterized by large‐scale disruptions in beta and gamma oscillations. Although subcortical beta power is an established biomarker for current adaptive deep brain stimulation (aDBS), it may not fully capture the global pathophysiological burden and the macroscale hierarchical reorganization of the ...
Hao Ding +8 more
wiley +1 more source
ABSTRACT Purpose To compare markers of cerebrovascular reactivity (CVR) measured with Gradient Echo (GE, T2*w) and Spin‐Echo (SE, T2w) BOLD fMRI with quantitative physiological CVR measured using ASL. Methods CVR, the ability of blood vessels to dilate and increase cerebral blood flow (CBF), can be investigated with ASL fMRI but has a low signal‐to ...
Sara Pomante +13 more
wiley +1 more source
Double Asymmetric Spin Echo EPI (dASE‐EPI) Enables fMRI of the Entire Rat Brain at 9.4 T
ABSTRACT Purpose Development and evaluation of a double asymmetric spin echo planar imaging (dASE‐EPI) sequence to balance sensitivity to blood oxygenation level‐dependent (BOLD) contrast with mitigation of susceptibility‐induced intravoxel spin dephasing in ultra high‐field rodent brain imaging.
Kyle A. Johnson +2 more
wiley +1 more source
Research status and trends of Piezo1 and brain: A bibliometric analysis
This graphical abstract illustrates the workflow and key findings of the bibliometric analysis of Piezo1 in brain research. The primary results were visually centered on a brain graphic highlighting the Piezo1 channel, and three converging research hotspots were identified: neurovascular regulation, calcium signaling, and neuroinflammation.
Yu Liu +8 more
wiley +1 more source
Activatable smart contrast agents for photoacoustic imaging
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh +5 more
wiley +1 more source

