Results 11 to 20 of about 28,046 (293)

Vasculo-Neuronal Coupling and Neurovascular Coupling at the Neurovascular Unit: Impact of Hypertension [PDF]

Frontiers in Physiology, 2020
Components of the neurovascular unit (NVU) establish dynamic crosstalk that regulates cerebral blood flow and maintain brain homeostasis. Here, we describe accumulating evidence for cellular elements of the NVU contributing to critical physiological ...
Jessica L. Presa, Jessica L. Presa, Flavia Saravia, Zsolt Bagi, Jessica A. Filosa   +4 more
doaj   +4 more sources

Measurement of Neurovascular Coupling in Neonates [PDF]

Frontiers in Physiology, 2019
Neurovascular coupling refers to the mechanism that links the transient neural activity to the subsequent change in cerebral blood flow, which is regulated by both chemical signals and mechanical effects.
Dries Hendrikx, Dries Hendrikx, Anne Smits, Anne Smits, Mario Lavanga, Mario Lavanga, Ofelie De Wel, Ofelie De Wel, Liesbeth Thewissen, Liesbeth Thewissen, Katrien Jansen, Katrien Jansen, Katrien Jansen, Alexander Caicedo, Sabine Van Huffel, Sabine Van Huffel, Gunnar Naulaers, Gunnar Naulaers   +17 more
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Neurovascular coupling mechanisms in health and neurovascular uncoupling in Alzheimer’s disease

Brain, 2022
AbstractTo match the metabolic demands of the brain, mechanisms have evolved to couple neuronal activity to vasodilation, thus increasing local cerebral blood flow and delivery of oxygen and glucose to active neurons. Rather than relying on metabolic feedback signals such as the consumption of oxygen or glucose, the main signalling pathways rely on the
Zhu, WM, Neuhaus, A, Beard, DJ, Sutherland, BA, DeLuca, GC   +4 more
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Disturbed neurovascular coupling in type 2 diabetes mellitus patients: Evidence from a comprehensive fMRI analysis

NeuroImage: Clinical, 2019
Background: Previous studies presumed that the disturbed neurovascular coupling to be a critical risk factor of cognitive impairments in type 2 diabetes mellitus (T2DM), but distinct clinical manifestations were lacked.
Bo Hu, Lin-Feng Yan, Qian Sun, Ying Yu, Jin Zhang, Yu-Jie Dai, Yang Yang, Yu-Chuan Hu, Hai-Yan Nan, Xin Zhang, Chun-Ni Heng, Jun-Feng Hou, Qing-Quan Liu, Chang-Hua Shao, Fei Li, Kai-Xiang Zhou, Hang Guo, Guang-Bin Cui, Wen Wang   +18 more
doaj   +3 more sources

Caveolae in CNS arterioles mediate neurovascular coupling

Nature, 2020
Proper brain function depends on neurovascular coupling: neural activity rapidly increases local blood flow to meet moment-to-moment changes in regional brain energy demand1. Neurovascular coupling is the basis for functional brain imaging2, and impaired neurovascular coupling is implicated in neurodegeneration1.
Chow, Brian W., Nuñez, Vicente, Kaplan, Luke, Granger, Adam J., Bistrong, Karina, Zucker, Hannah L., Kumar, Payal, Sabatini, Bernardo L., Gu, Chenghua   +8 more
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Neurovascular coupling during deep brain stimulation [PDF]

Brain Stimulation, 2020
Background: Deep brain stimulation (DBS) is an effective treatment for movement disorders, yet its mechanisms of action remain unclear. One method used to study its circuit-wide neuromodulatory effects is functional magnetic resonance imaging (fMRI ...
M. Sohail Noor, Linhui Yu, Kartikeya Murari, Zelma HT. Kiss   +3 more
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Retinal Neurovascular Coupling in Diabetes [PDF]

Journal of Clinical Medicine, 2020
Neurovascular coupling, also termed functional hyperemia, is one of the physiological key mechanisms to adjust blood flow in a neural tissue in response to functional activity. In the retina, increased neural activity, such as that induced by visual stimulation, leads to the dilatation of retinal arterioles, which is accompanied by an immediate ...
Gerhard Garhöfer, Jacqueline Chua, Bingyao Tan, Damon Wong, Doreen Schmidl, Leopold Schmetterer   +5 more
openaire   +3 more sources

Neurovascular coupling in bone regeneration

Experimental & Molecular Medicine, 2022
AbstractThe mammalian skeletal system is densely innervated by both neural and vascular networks. Peripheral nerves in the skeleton include sensory and sympathetic nerves. The crosstalk between skeletal and neural tissues is critical for skeletal development and regeneration.
Qizhi Qin, Seungyong Lee, Nirali Patel, Kalah Walden, Mario Gomez-Salazar, Benjamin Levi, Aaron W. James   +6 more
openaire   +2 more sources

Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice

Communications Biology, 2023
In the adult sensory cortex, increases in neural activity elicited by sensory stimulation usually drive vasodilation mediated by neurovascular coupling.
Kyle W. Gheres, Hayreddin S. Ünsal, Xu Han, Qingguang Zhang, Kevin L. Turner, Nanyin Zhang, Patrick J. Drew   +6 more
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Altered resting-state neurovascular coupling in patients with pontine infarction

Experimental Gerontology, 2023
The risk for motor and cognitive impairment is increased in patients with chronic pontine infarction (PI). In this study, we attempted to explore the alterations of neurovascular coupling (NVC) in order to understand the neural basis of behavioral ...
Peipei Wang, Caihong Wang, Yong Zhang, Peifang Miao, Jingchun Liu, Sen Wei, Yarui Wei, Shaoqiang Han, Xin Wang, Yingying Wang, Luobing Wu, Kaiyu Wang, Jingliang Cheng, Ying Wei   +13 more
doaj   +1 more source