Results 31 to 40 of about 14,410 (259)

Spreading Depression and Neurovascular Coupling [PDF]

open access: yesStroke, 2013
Spreading depression, discovered by Leao in 1944,1 is an intense depolarization wave that slowly propagates (≈3 mm/min) in gray matter by way of contiguity, regardless of functional divisions or arterial territories. The depolarization is associated with massive transmembrane ionic and water shifts coupled to a surge in extracellular K+ and ...
openaire   +2 more sources

The Oxygen Paradox of Neurovascular Coupling [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 2013
The coupling of cerebral blood flow (CBF) to neuronal activity is well preserved during evolution. Upon changes in the neuronal activity, an incompletely understood coupling mechanism regulates diameter changes of supplying blood vessels, which adjust CBF within seconds.
Christoph, Leithner, Georg, Royl
openaire   +2 more sources

Neurovascular coupling is preserved in chronic stroke recovery after targeted photothrombosis

open access: yesNeuroImage: Clinical, 2023
Functional neuroimaging, which measures hemodynamic responses to brain activity, has great potential for monitoring recovery in stroke patients and guiding rehabilitation during recovery.
Smrithi Sunil   +8 more
doaj   +1 more source

Neurovascular Decoupling Is Associated With Lobar Intracerebral Hemorrhages and White Matter Hyperintensities

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Neurovascular coupling is a fundamental aspect of brain function by regulating cerebral blood flow in response to regional neuronal activity.
Suzanne E. van Dijk   +10 more
doaj   +1 more source

Brain capillary pericytes and neurovascular coupling

open access: yesComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2021
The neurovascular coupling ensures that cerebral activity is matched by the relevant blood flow. The control of the blood flow is mediated by capillaries and by the precapillary aterioles. It is the tone of the mural cells, which include pericytes, smooth muscle cells and cells with intermediate phenotypes between pericytes and smooth muscle cells ...
Grubb, Søren   +2 more
openaire   +4 more sources

Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications

open access: yesFrontiers in Endocrinology, 2022
Type 2 diabetes causes substantial long-term damage in several organs including the brain. Cognitive decline is receiving increased attention as diabetes has been established as an independent risk factor along with the identification of several other ...
Mads C. J. Barloese   +11 more
doaj   +1 more source

Non-invasive, multimodal analysis of cortical activity, blood volume and neurovascular coupling in infantile spasms using EEG-fNIRS monitoring

open access: yesNeuroImage: Clinical, 2017
Although infantile spasms can be caused by a variety of etiologies, the clinical features are stereotypical. The neuronal and vascular mechanisms that contribute to the emergence of infantile spasms are not well understood.
Emilie Bourel-Ponchel   +4 more
doaj   +1 more source

Integrative neurovascular coupling and neurotransmitter analyses in anisometropic and visual deprivation amblyopia children

open access: yesiScience
Summary: The association between visual abnormalities and impairments in cerebral blood flow and brain region potentially results in neural dysfunction of amblyopia. Nevertheless, the differences in the complex mechanisms of brain neural network coupling
Xiaopan Zhang   +10 more
doaj   +1 more source

Assessment of neurovascular coupling and cortical spreading depression in mixed mouse models of atherosclerosis and Alzheimer’s disease

open access: yeseLife, 2022
Neurovascular coupling is a critical brain mechanism whereby changes to blood flow accompany localised neural activity. The breakdown of neurovascular coupling is linked to the development and progression of several neurological conditions including ...
Osman Shabir   +11 more
doaj   +1 more source

Investigating the Limits of Neurovascular Coupling [PDF]

open access: yesNeuron, 2016
O'Herron et al. (2016) perform two-photon imaging of vascular and neural responses in cat and rodent primary visual cortex to investigate the limits of neurovascular coupling. Their results suggest important constraints on making inferences about neuronal responses from hemodynamic activity.
George H, Denfield   +3 more
openaire   +2 more sources

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