Results 51 to 60 of about 15,500 (253)

Hard‐Magnetic Soft Millirobots in Underactuated Systems

Advanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang, Zixuan Zhang, Bingyan Li, Junkai Wang, Hongcheng Gu   +4 more
wiley   +1 more source

Control of the neurovascular coupling by nitric oxide-dependent regulation of astrocytic Ca2+ signaling

Frontiers in Cellular Neuroscience, 2015
Neuronal activity must be tightly coordinated with blood flow to keep proper brain function, which is achieved by a mechanism known as neurovascular coupling. Then, an increase in synaptic activity leads to a dilation of local parenchymal arterioles that
Manuel Francisco Muñoz, Mariela ePuebla, Xavier eFigueroa   +2 more
doaj   +1 more source

A Superlubricated Magnetically Steerable Microcatheter with Integrated Optical and Fluidic Channels

Advanced Robotics Research, EarlyView.
A magnetically steerable microcatheter with integrated optical and fluidic channels is developed for multifunctional navigation in tortuous anatomical environments. A surface‐grafted hydrogel coating enables low‐friction actuation. The device demonstrates stable light and fluid delivery during magnetic manipulation, offering a compact platform for ...
Yuntian Du, Ruokun He, Luqi Li, Hesheng Wang, Zhuo‐Chen Ma, Bing Han   +5 more
wiley   +1 more source

Altered dynamics of neurovascular coupling in CADASIL [PDF]

Annals of Clinical and Translational Neurology, 2018
AbstractBackground and ObjectiveNeurovascular coupling is the complex biological process that underlies use‐dependent increases in blood flow in response to neural activation. Neurovascular coupling was investigated at the early stage of CADASIL, a genetic paradigm of ischemic small vessel disease.MethodsFunctional hyperemia and evoked potentials ...
Huneau, Clément, Houot, Marion, Joutel, Anne, Béranger, Benoit, Giroux, Christian, Benali, Habib, Chabriat, Hugues   +6 more
openaire   +4 more sources

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Advances in the study of neurovascular coupling in bone repair

Shanghai Jiaotong Daxue xuebao. Yixue ban
Bone repair is a complex physiological process. The nerves within the bone can regulate bone tissue regeneration through the secretion of bioactive factors and interactions with cells within the bone. Recent studies have sought to leverage the principles
HE Shuhang, GUO Shangchun, TAO Shicong
doaj   +1 more source

Neurovascular Uncoupling Is Linked to Microcirculatory Dysfunction in Regions Outside the Ischemic Core Following Ischemic Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Normal brain function depends on the ability of the vasculature to increase blood flow to regions with high metabolic demands. Impaired neurovascular coupling, such as the local hyperemic response to neuronal activity, may contribute to poor ...
Christian Staehr, John T. Giblin, Eugenio Gutiérrez‐Jiménez, Halvor Ø. Guldbrandsen, Jianbo Tang, Shaun L. Sandow, David A. Boas, Vladimir V. Matchkov   +7 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus

Frontiers in Physiology, 2018
Neurovascular and neurometabolic coupling are critical and complex processes underlying brain function. Perturbations in the regulation of these processes are, likely, early dysfunctional alterations in pathological brain aging and age-related ...
Cátia F. Lourenço, Ana Ledo, Miguel Caetano, Rui M. Barbosa, Rui M. Barbosa, João Laranjinha, João Laranjinha   +6 more
doaj   +1 more source