Results 51 to 60 of about 924,446 (277)

Neurovascular Decoupling Is Associated With Lobar Intracerebral Hemorrhages and White Matter Hyperintensities

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Neurovascular coupling is a fundamental aspect of brain function by regulating cerebral blood flow in response to regional neuronal activity.
Suzanne E. van Dijk, Nadieh Drenth, Anne Hafkemeijer, Gerda Labadie, Marie‐Noëlle W. Witjes‐Ané, Frank Baas, Jeroen P. Vreijling, Gerard J. Blauw, Serge A. R. B. Rombouts, Jeroen van der Grond, Sanneke van Rooden   +10 more
doaj   +1 more source

Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus

Frontiers in Neuroscience, 2022
ObjectiveAltered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients.Materials and MethodsTwenty-four right PT ...
Xiaoshuai Li, Ning Xu, Chihang Dai, Xuxu Meng, Xiaoyu Qiu, Heyu Ding, Rong Zeng, Han Lv, Pengfei Zhao, Zhenghan Yang, Shusheng Gong, Zhenchang Wang   +11 more
doaj   +1 more source

Neurovascular coupling is preserved in chronic stroke recovery after targeted photothrombosis

NeuroImage: Clinical, 2023
Functional neuroimaging, which measures hemodynamic responses to brain activity, has great potential for monitoring recovery in stroke patients and guiding rehabilitation during recovery.
Smrithi Sunil, John Jiang, Shashwat Shah, Sreekanth Kura, Kivilcim Kilic, Sefik Evren Erdener, Cenk Ayata, Anna Devor, David A. Boas   +8 more
doaj   +1 more source

Integrative neurovascular coupling and neurotransmitter analyses in anisometropic and visual deprivation amblyopia children

iScience
Summary: The association between visual abnormalities and impairments in cerebral blood flow and brain region potentially results in neural dysfunction of amblyopia. Nevertheless, the differences in the complex mechanisms of brain neural network coupling
Xiaopan Zhang, Liang Liu, Yadong Li, Xiao Li, Kejia Wang, Shaoqiang Han, Mengzhu Wang, Yong Zhang, Guangying Zheng, Jingliang Cheng, Baohong Wen   +10 more
doaj   +1 more source

Non-invasive, multimodal analysis of cortical activity, blood volume and neurovascular coupling in infantile spasms using EEG-fNIRS monitoring

NeuroImage: Clinical, 2017
Although infantile spasms can be caused by a variety of etiologies, the clinical features are stereotypical. The neuronal and vascular mechanisms that contribute to the emergence of infantile spasms are not well understood.
Emilie Bourel-Ponchel, Mahdi Mahmoudzadeh, Aline Delignières, Patrick Berquin, Fabrice Wallois   +4 more
doaj   +1 more source

Autoregulation of the Human Cerebrovasculature by Neurovascular Coupling [PDF]

, 2013
Functional hyperaemia is an important mechanism by which increased neuronal activity is matched by a rapid and regional increase in blood supply.
Farr, Hannah Abigail
core   +1 more source

Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications

Frontiers in Endocrinology, 2022
Type 2 diabetes causes substantial long-term damage in several organs including the brain. Cognitive decline is receiving increased attention as diabetes has been established as an independent risk factor along with the identification of several other ...
Mads C. J. Barloese, Mads C. J. Barloese, Christian Bauer, Christian Bauer, Esben Thade Petersen, Esben Thade Petersen, Christian Stevns Hansen, Sten Madsbad, Sten Madsbad, Hartwig Roman Siebner, Hartwig Roman Siebner, Hartwig Roman Siebner   +11 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Neurovascular coupling in eye-open-eye-close task and resting state: Spectral correspondence between concurrent EEG and fMRI

NeuroImage
Neurovascular coupling serves as an essential neurophysiological mechanism in functional neuroimaging, which is generally presumed to be robust and invariant across different physiological states, encompassing both task engagement and resting state ...
Yi-Chia Kung, Chia-Wei Li, Ai-Ling Hsu, Chi-Yun Liu, Changwei W. Wu, Wei-Chou Chang, Ching-Po Lin   +6 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source