Results 71 to 80 of about 17,591 (285)

Image_6_Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus.JPEG

, 2022
ObjectiveAltered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients.Materials and MethodsTwenty-four right PT ...
Xiaoyu Qiu (1939150), Rong Zeng (54019), Zhenchang Wang (771972), Ning Xu (52890), Heyu Ding (11807462), Chihang Dai (11807459), Xiaoshuai Li (5854538), Shusheng Gong (577362), Xuxu Meng (11807456), Han Lv (537263), Pengfei Zhao (701271), Zhenghan Yang (8978279)   +11 more
core   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Unraveling the brain's response to hypoglycemia : Neurovascular coupling

Functional magnetic resonance imaging has suggested the possibility that hypoglycemia could interfere with neurovascular coupling. Here we discuss the implications of a study by Nippert and colleagues showing that hypoglycemia does not impair ...
Duarte, João Mn, Schwaninger, Markus
core   +2 more sources

Image_5_Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus.JPEG

, 2022
ObjectiveAltered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients.Materials and MethodsTwenty-four right PT ...
Xiaoyu Qiu (1939150), Rong Zeng (54019), Zhenchang Wang (771972), Ning Xu (52890), Heyu Ding (11807462), Chihang Dai (11807459), Xiaoshuai Li (5854538), Shusheng Gong (577362), Xuxu Meng (11807456), Han Lv (537263), Pengfei Zhao (701271), Zhenghan Yang (8978279)   +11 more
core   +1 more source

Neurovascular Uncoupling Is Linked to Microcirculatory Dysfunction in Regions Outside the Ischemic Core Following Ischemic Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Normal brain function depends on the ability of the vasculature to increase blood flow to regions with high metabolic demands. Impaired neurovascular coupling, such as the local hyperemic response to neuronal activity, may contribute to poor ...
Christian Staehr, John T. Giblin, Eugenio Gutiérrez‐Jiménez, Halvor Ø. Guldbrandsen, Jianbo Tang, Shaun L. Sandow, David A. Boas, Vladimir V. Matchkov   +7 more
doaj   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus

Frontiers in Physiology, 2018
Neurovascular and neurometabolic coupling are critical and complex processes underlying brain function. Perturbations in the regulation of these processes are, likely, early dysfunctional alterations in pathological brain aging and age-related ...
Cátia F. Lourenço, Ana Ledo, Miguel Caetano, Rui M. Barbosa, Rui M. Barbosa, João Laranjinha, João Laranjinha   +6 more
doaj   +1 more source

Image_3_Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus.JPEG

, 2022
ObjectiveAltered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients.Materials and MethodsTwenty-four right PT ...
Xiaoyu Qiu (1939150), Rong Zeng (54019), Zhenchang Wang (771972), Ning Xu (52890), Heyu Ding (11807462), Chihang Dai (11807459), Xiaoshuai Li (5854538), Shusheng Gong (577362), Xuxu Meng (11807456), Han Lv (537263), Pengfei Zhao (701271), Zhenghan Yang (8978279)   +11 more
core   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

The effect of different anesthetics on neurovascular coupling [PDF]

NeuroImage, 2010
To date, the majority of neurovascular coupling studies focused on the thalamic afferents' activity in layer IV and the corresponding large spiking activity as responsible for functional hyperemia. This paper highlights the role of the secondary and late cortico-cortical transmission in neurovascular coupling. Simultaneous scalp electroencephalography (
Maria Angela Franceschini, Harsha Radhakrishnan, Kiran Thakur, Weicheng Wu, Svetlana Ruvinskaya, Stefan A. Carp, David A. Boas   +6 more
openaire   +2 more sources