Results 81 to 90 of about 17,591 (285)

Modeling the relationship between neuronal activity and the BOLD signal: contributions from astrocyte calcium dynamics

Scientific Reports, 2023
Functional magnetic resonance imaging relies on the coupling between neuronal and vascular activity, but the mechanisms behind this coupling are still under discussion.
Federico Tesler, Marja-Leena Linne, Alain Destexhe   +2 more
doaj   +1 more source

Image_8_Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus.JPEG

, 2022
ObjectiveAltered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients.Materials and MethodsTwenty-four right PT ...
Xiaoyu Qiu (1939150), Rong Zeng (54019), Zhenchang Wang (771972), Ning Xu (52890), Heyu Ding (11807462), Chihang Dai (11807459), Xiaoshuai Li (5854538), Shusheng Gong (577362), Xuxu Meng (11807456), Han Lv (537263), Pengfei Zhao (701271), Zhenghan Yang (8978279)   +11 more
core   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Altered neurovascular coupling in neuromyelitis optica [PDF]

Human Brain Mapping, 2018
AbstractNeurovascular coupling reflects the close relationship between neuronal activity and cerebral blood flow (CBF), providing a new mechanistic insight into health and disease. Neuromyelitis optica (NMO) is an autoimmune inflammatory demyelinating disease of the central nervous system and shows cognitive decline‐related brain gray matter ...
Xi Guo, Jiajia Zhu, Ningnannan Zhang, Linjie Zhang, Yuan Qi, Huanhuan Cai, Xue Zhang, Jie Sun, Qiuhui Wang, Li Yang, Fu‐Dong Shi, Chunshui Yu   +11 more
openaire   +2 more sources

Lower neurovascular coupling response despite higher cerebral blood flow at rest in apolipoprotein ɛ4 positive adults.

PLoS ONE
Cerebral blood flow at rest declines with age. However, age-related changes in functional measures of cerebrovascular health including cerebrovascular reactivity and neurovascular coupling are not well understood.
Andrew G Pearson, Kathleen B Miller, Adam T Corkery, Nicole A Loggie, Anna J Howery, Leonardo A Rivera-Rivera, Oliver Wieben, Kevin M Johnson, Sterling C Johnson, Jill N Barnes   +9 more
doaj   +1 more source

Neurovascular coupling during deep brain stimulation

Brain Stimulation, 2020
Background: Deep brain stimulation (DBS) is an effective treatment for movement disorders, yet its mechanisms of action remain unclear. One method used to study its circuit-wide neuromodulatory effects is functional magnetic resonance imaging (fMRI ...
M. Sohail Noor, Linhui Yu, Kartikeya Murari, Zelma HT. Kiss   +3 more
doaj   +1 more source

Developing Methodologies to Explore Neurovascular Coupling on a Micron Scale

, 2016
During brain activity, local oxygen and glucose is consumed and cerebral blood flow (CBF) increases in a process known as functional hyperemia or neurovascular coupling.
Walton, Lindsay
core   +1 more source

Neurovascular coupling in a central nervous system white matter tract

, 2022
Neurovascular coupling is the process by which blood vessels dilate upon increased neuronal activity. It has been extensively studied in the murine grey matter and there are several models explaining possible molecular and cellular pathways that ...
Restrepo Arango, Alejandro
core   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Anesthesia and the Quantitative Evaluation of Neurovascular Coupling [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2012
Anesthesia has broad actions that include changing neuronal excitability, vascular reactivity, and other baseline physiologies and eventually modifies the neurovascular coupling relationship. Here, we review the effects of anesthesia on the spatial propagation, temporal dynamics, and quantitative relationship between the neural and vascular responses ...
Kazuto, Masamoto, Iwao, Kanno
openaire   +2 more sources