Results 121 to 130 of about 2,245,425 (289)

Cardiovascular and Neurovascular Imaging: Physics and Technology

, 2015
Cardiovascular and Neurovascular Imaging: Physics and Technology explains the underlying physical and technical principles behind a range of cardiovascular and neurovascular imaging modalities, including radiography, nuclear medicine, ultrasound, and ...
Cavedon, Carlo, Rudin, Stephen, Carlo Cavedon, Stephen Rudin   +2 more
core   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

Cryo-EM structures of mouse bestrophin 1 channel in closed and partially open conformations

Molecules and Cells
: Bestrophin 1 (BEST1) channels are calcium-activated Cl− channels involved in diverse physiological processes, including gliotransmitter release in astrocytes.
Kwon-Woo Kim, Euna Lee, Ara Ko, Junmo Hwang, Kunwoong Park, Byoung-Cheol Lee, Ki Woo Kim, Won-Jong Oh, Kyuhyung Kim, Hyun-Ho Lim   +9 more
doaj   +1 more source

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

Advanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee, Chan Ho Jeon, Doyun Kim, Minjae Lee, Minji Kwon, Joon Myong Song   +5 more
wiley   +1 more source

SEMA3E-PLEXIN-D1 AXON GUIDANCE SIGNALING ENHANCES MTSS1 EXPRESSION TO REGULATE PROPER STRIATONIGRAL PROJECTION

IBRO Neuroscience Reports, 2023
Won-Jong Oh, Yan Li, Namsuk Kim
doaj   +1 more source

Revolutionizing Ischemic Stroke Diagnosis and Treatment: The Promising Role of Neurovascular Unit-Derived Extracellular Vesicles

Ischemic stroke is a fatal and disabling disease worldwide and imposes a significant burden on society. At present, biological markers that can be conveniently measured in body fluids are lacking for the diagnosis of ischemic stroke, and there are no ...
Xiangyu Gao, Dan Liu, Xiaofan Jiang, Zhuoyuan Zhang, Peng Luo, Kangyi Yue   +5 more
core   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

Advanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li, Zhikun Miao, Tuck‐Whye Wong, Tiefeng Li   +3 more
wiley   +1 more source

Statistical analysis plan for the multicenter, open, randomized controlled clinical trial to assess the efficacy and safety of intravenous tirofiban vs aspirin in acute ischemic stroke due to tandem lesion, undergoing recanalization therapy by endovascular treatment (ATILA trial)

Trials
Rationale In-stent reocclusion after endovascular therapy has a negative impact on outcomes in acute ischemic stroke (AIS) due to tandem lesions (TL).
Elena Zapata-Arriaza, Manuel Medina-Rodríguez, Francisco Moniche Álvarez, Asier de Albóniga-Chindurza, Marta Aguilar-Pérez, Leire Ainz-Gómez, Pablo Baena-Palomino, Aynara Zamora, Blanca Pardo-Galiana, Fernando Delgado-Acosta, Roberto Valverde Moyano, Elvira Jiménez-Gómez, Isabel Bravo Rey, Rafael Oteros Fernández, Irene Escudero-Martínez, Isabel Vielba-Gomez, Lluis Morales Caba, Jose Díaz Pérez, Estefania García Molina, Sonia Mosteiro, María del Mar Castellanos Rodrigo, Laura Amaya Pascasio, Carlos Hidalgo, María del Mar Freijo Guerrero, Eva González Díaz, Jose María Ramírez Moreno, Luis Fernández Prudencio, Mikel Terceño Izaga, Saima Bashir Viturro, Miguel Ángel Gamero-García, Silvia Jiménez Jorge, Clara Rosso Fernández, Joan Montaner, Alejandro González García   +33 more
doaj   +1 more source

Patient-reported symptoms and admission pathways in stroke mimics versus confirmed stroke or transient ischaemic attack: a cross-sectional observational study

BMJ Open
Objectives To determine patient-reported symptoms and clinical factors associated with mimics and differences in health-seeking behaviour versus stroke.Design This is a post-hoc analysis of a cross-sectional survey of interviews on patient-reported ...
Jawad Haider Butt, Christina Kruuse, Heidi Shil Eddelien, Viktor Frederik Idin Sørensen   +3 more
doaj   +1 more source

Cellular Mechanisms of Neurovascular Damage and Repair After Stroke

, 2011
The biological processes underlying stroke are complex, and patients have a narrow repertoire of therapeutic opportunities. After the National Institutes of Health (NIH) convened the Stroke Progress Review Group in 2001, stroke research shifted from ...
Josephine Lok, Ken Arai, Changhong Xing, Eng H. Lo, Shuzhen Guo, Kazuhide Hayakawa   +5 more
core   +1 more source