Results 101 to 110 of about 2,245,425 (289)

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Table_1_Aging Neurovascular Unit and Potential Role of DNA Damage and Repair in Combating Vascular and Neurodegenerative Disorders.DOCX

, 2019
Progressive neurological deterioration poses enormous burden on the aging population with ischemic stroke and neurodegenerative disease patients, such as Alzheimers’ disease and Parkinson’s disease. The past two decades have witnessed remarkable advances
Peiying Li (797714), Yueman Zhang (7160432), Tingting Huang (496866), Yan Li (23143), Lv Xie (5872859), Bo Qi (630839), Xin Wang (91924), Zengai Chen (7160435), Jie Zhou (28945)   +8 more
core   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Correction: Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine

The Journal of Headache and Pain, 2023
Rosaria Greco, Miriam Francavilla, Chiara Demartini, Anna Maria Zanaboni, Mikael H. Sodergren, Sara Facchetti, Barbara Pacchetti, Michela Palmisani, Valentina Franco, Cristina Tassorelli   +9 more
doaj   +1 more source

Is canonical SD a clinically relevant model of migraine? Argument pro

The Journal of Headache and Pain
Migraine with aura is a phenotypically heterogeneous disorder characterized by scintillating scotoma, sensory, language, and/or motor disturbance often followed by a severe headache, and cutaneous allodynia.
Muhammed Miran Oncel, Andrea M. Harriott
doaj   +1 more source

Raw data for 'Layer-specific anatomical and physiological features of the retina’s neurovascular unit'

Raw data for Current Biology article entitled 'Layer-specific anatomical and physiological features of the retina’s neurovascular unit'
Grimes, William
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Recommendations for the neurovascular units

, 2003
Recommendations for the neurovascular ...
P Desfontaines (13444668), G Vanhooren (13445160), A Peeters (9174206), P Laloux (13444674)   +3 more
core  

Early Clinical Experiences with Positron Emission Tomography–Magnetic Resonance Imaging in Epilepsy: Implications for Modeling the Neurovascular Unit

, 2017
Cortical function in normal and pathologic neurologic states is largely influenced by the activity of the neurovascular unit. Hybrid technologies that combine positron emission tomography and magnetic resonance imaging (PET/MRI) offer a chance for ...
Justin Brucker, Alok Bhatt
core   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source