Results 101 to 110 of about 4,031,569 (323)
Neural Regeneration Research, 2019 Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit.
Jian Liu +6 more
doaj +1 more source
Subarachnoid Haemorrhage in Malta : Are outcomes adversely affected due to lack of a local neurovascular service? [PDF]
, 2014 Objective: This study was performed to assess the incidence, treatment and outcome of non-traumatic Subarachnoid Haemorrhage (SAH) in an island which does not offer a neurovascular service and to determine whether such limitation is associated with a ...
Aquilina, Josanne +4 more
core
VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels [PDF]
, 2017 We thank Vann Bennett and Daizing Zhou (Department of Biochemistry, Duke University Medical Center) for the design and generation of the Brn3bCre knock-in mice.
Bruce, Freyja +7 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source
Gene therapy for neurovascular unit
Nosotchu, 2007 Gene transfer technique may be applicable to the treatment of serious types of brain infarction. Recently the neurovascular unit is proposed as an important target for brain infarction. Therefore, we examined usefulness of gene transfer approach for neurovascular protection in brain ischemia.
Hiroaki Ooboshi, Setsuro Ibayashi
openaire +2 more sources
Targeting the Neurovascular Unit in Brain Trauma [PDF]
CNS Neuroscience & Therapeutics, 2014 SummaryAlthough the neurovascular unit was originally developed as a conceptual framework for stroke, it is now recognized that these cell–cell interactions play critical roles in many other CNS disorders as well. In brain trauma, perturbations within the neurovascular unit may be especially important.
Josephine, Lok +10 more
openaire +2 more sources
Neurovascular Coupling in Development and Disease: Focus on Astrocytes
Frontiers in Cell and Developmental Biology, 2021 Neurovascular coupling is a crucial mechanism that matches the high energy demand of the brain with a supply of energy substrates from the blood. Signaling within the neurovascular unit is responsible for activity-dependent changes in cerebral blood flow.
Teresa L. Stackhouse +2 more
doaj +1 more source
Dual-function injectable angiogenic biomaterial for the repair of brain tissue following stroke. [PDF]
, 2018 Stroke is the primary cause of disability due to the brain's limited ability to regenerate damaged tissue. After stroke, an increased inflammatory and immune response coupled with severely limited angiogenesis and neuronal growth results in a stroke ...
Carmichael, S Thomas +3 more
core +1 more source
BiomoleculesIschemic stroke is a fatal and disabling disease worldwide and imposes a significant burden on society. At present, biological markers that can be conveniently measured in body fluids are lacking for the diagnosis of ischemic stroke, and there are no ...
Xiangyu Gao +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source