Results 11 to 20 of about 38,595 (171)
Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase. [PDF]
PLoS ONE, 2009 BackgroundNeutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-beta (Abeta) degradation.
Thomas Walther +13 more
doaj +2 more sources
Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice [PDF]
Journal of Obesity, 2012 We have demonstrated that treating diet-induced obese (DIO) mice with the vasopeptidase inhibitor ilepatril improved neural function. Vasopeptidase inhibitors block angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) activity.
Lawrence Coppey +3 more
doaj +2 more sources
Expression of Neutral Endopeptidase, Endothelin-1, and Nuclear Factor Kappa B in Prostate Cancer: Interrelations and Associations with Prostate-Specific Antigen Recurrence after Radical Prostatectomy [PDF]
Prostate Cancer, 2012 Objective. To study the impact of the neutral endopeptidase (NEP)/neuropeptides (NPs) axis and nuclear factor kappa B (NFκB) as predictors of prostate-specific antigen (PSA) recurrence after radical prostatectomy (RP). Patients and Methods.
Panagiotis J. Vlachostergios +9 more
doaj +2 more sources
Serum neprilysin levels are elevated in preeclampsia
Taiwanese Journal of Obstetrics & Gynecology, 2021 Objective: To evaluate the possible associations between serum Neprilysin (NEP) levels and preeclampsia and mild and severe preeclampsia subgroups. Materials and methods: Fifty-five consecutive women with mild preeclampsia and fifty-five consecutive ...
Nevin Tüten +8 more
doaj +1 more source
Metabolism of renin-angiotensin and enkephalin in human follicular fluid: An experimental study
International Journal of Reproductive BioMedicine, 2022 Background: The relationship between the biochemical characteristics of follicular fluid (FF), oocyte quality and embryonic development has not yet been elucidated.
Maria Victoria Rodríguez Gallego +5 more
doaj +1 more source
Neutral endopeptidase expression in mesangial cells [PDF]
Journal of the Renin-Angiotensin-Aldosterone System, 2003 In the kidney, neutral endopeptidase (NEP) is implicated in the metabolism of several peptides involved in blood pressure and sodium homeostasis control, such as the atrial natriuretic peptide, bradykinin and angiotensin I. Due to its physiological importance in the modulation of pressor responses, the presence of NEP in mouse mesangial cells has been
Fabiana, Ebihara +3 more
openaire +5 more sources
Clinical and Translational Allergy, 2021 Background Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the
Olivia Larsson +4 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 1997 Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
M.A.S. Medeiros +4 more
doaj +1 more source
Frontiers in Plant Science, 2023 Citrus, one of the most widely cultivated fruit crops in the world, relies on arbuscular mycorrhizal fungi (AMF) to absorb nutrients and water from soil.
Huimin Yu +6 more
doaj +1 more source
Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase
Neurobiology of Disease, 2009 The complex regional pain syndrome (CRPS) is characterized by enhanced neurogenic inflammation, mediated by neuropeptides. Neutral endopeptidase (NEP) is a key enzyme in neuropeptide catabolism.
Heidrun H. Krämer +4 more
doaj +1 more source