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Testing the neutral hypothesis of phenotypic evolution [PDF]

open access: yesProceedings of the National Academy of Sciences, 2016
SignificanceDespite the universal recognition that adaptation by Darwinian selection can shape phenotypic variations within and between species, it remains unknown whether most phenotypic variations observed have adaptive values, in part because addressing this question requires examining a large, random set of traits while past studies were biased ...
Wei-Chin Ho   +2 more
openaire   +4 more sources

Evaluation of immunogenicity of the 2008-2009 seasonal influenza vaccines by microneutralization test [PDF]

open access: yesKorean Journal of Pediatrics, 2012
PurposeFor evaluating the immunogenicity of an influenza vaccine, the microneutralization (MN) test has a higher sensitivity and specificity as compared to the hemagglutination inhibition (HI) test.
Seung Youn Kim   +8 more
doaj   +1 more source

The methods for removal of direct oral anticoagulants and heparins to improve the monitoring of hemostasis: a narrative literature review

open access: yesThrombosis Journal, 2023
The assessment of hemostasis is necessary to make suitable decisions on the management of patients with thrombotic disorders. In some clinical situations, for example, during thrombophilia screening, the presence of anticoagulants in sample makes ...
Aleksandra Frackiewicz   +3 more
doaj   +1 more source

Evaluation of high-throughput SARS-CoV-2 serological assays in a longitudinal cohort of patients with mild COVID-19: clinical sensitivity, specificity and association with virus neutralization test.

open access: yesClinical Chemistry, 2021
BACKGROUND The association between SARS-CoV-2 commercial serological assays and virus neutralization test (VNT) has been poorly explored in mild patients with COVID-19.
A. Bal   +18 more
semanticscholar   +1 more source

TESTING NEUTRALITY IN SUBDIVIDED POPULATIONS [PDF]

open access: yesGenetics, 1982
ABSTRACT Statistical tests of the neutrality hypothesis that are based on the sampling theory of Ewens (1972) require the assumption of panmixia. It is proposed that for a population comprising numerous local populations with weak gene flow among them, tests based on Ewens' theory can be applied separately to samples from each local ...
openaire   +3 more sources

International proficiency trial for bovine viral diarrhea virus (BVDV) antibody detection: limitations of milk serology

open access: yesBMC Veterinary Research, 2022
Background Control programs were implemented in several countries against bovine viral diarrhea (BVD), one of the most significant cattle diseases worldwide. Most of the programs rely on serological diagnostics in any phase of the program.
Kerstin Wernike, Martin Beer
doaj   +1 more source

Kinetics of Neutralizing Antibodies of COVID-19 Patients Tested Using Clinical D614G, B.1.1.7, and B 1.351 Isolates in Microneutralization Assays

open access: yesViruses, 2021
Increasing evidence suggests that some newly emerged SARS-CoV-2 variants of concern (VoCs) resist neutralization by antibodies elicited by the early-pandemic wild-type virus.
Jenni Virtanen   +16 more
doaj   +1 more source

Serological evidence of SARS-CoV-2 infection in dromedary camels and domestic bovids in Oman

open access: yesEmerging Microbes and Infections, 2023
SARS-CoV-2 has demonstrated the ability to infect a wide range of animal species. Here, we investigated SARS-CoV-2 infection in livestock species in Oman and provided serological evidence of SARS-CoV-2 infection in cattle, sheep, goats, and dromedary ...
Ihab El Masry   +12 more
doaj   +1 more source

Evaluation of Chimeric Japanese Encephalitis and Dengue Viruses for Use in Diagnostic Plaque Reduction Neutralization Tests

open access: yesClinical and Vaccine Immunology, 2009
The plaque reduction neutralization test (PRNT) is a specific serological test used to identify and confirm arbovirus infection in diagnostic laboratories and monitor immunological protection in vaccine recipients. Wild-type (wt) viruses used in the PRNT
B. W. Johnson   +6 more
semanticscholar   +1 more source

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