Results 191 to 200 of about 1,883,437 (383)

In silico analysis suggests less effective MHC-II presentation of SARS-CoV-2 RBM peptides: Implication for neutralizing antibody responses

, 2021
Andrea Castro, Kıvılcım Öztürk, Maurizio Zanetti, Hannah Carter   +3 more
openalex   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Molecular convergence of neutralizing antibodies in human revealed by repeated rabies vaccination

npj Vaccines
Rabies vaccines require repeated immunization to robustly elicit neutralizing antibodies that prevent fatal diseases. Here, we analyzed rabies glycoprotein antibody repertoires at both polyclonal and monoclonal levels following repeated vaccination ...
Mizuki Fujisawa, Taishi Onodera, Daisuke Kuroda, Chidchamai Kewcharoenwong, Michihito Sasaki, Yukari Itakura, Kohei Yumoto, Arnone Nithichanon, Naoto Ito, Shinji Takeoka, Tadaki Suzuki, Hirofumi Sawa, Ganjana Lertmemongkolchai, Yoshimasa Takahashi   +13 more
doaj   +1 more source

Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies [PDF]

, 2018
Batsirai Mabvakure, Cathrine Scheepers, Nigel Garrett, Salim S. Abdool Karim, Carolyn Williamson, Lynn Morris, Penny L. Moore   +6 more
openalex   +1 more source

Development of a Novel Chikungunya Virus-Like Replicon Particle for Rapid Quantification and Screening of Neutralizing Antibodies and Antivirals

, 2023
Hui-Chung Lin, Der-Jiang Chiao, Pei‐Yun Shu, Hui‐Tsu Lin, Chia-Chu Hsiung, Chang-Chi Lin, Szu-Cheng Kuo   +6 more
openalex   +1 more source

Reduced neutralizing antibody response to SARS‐CoV‐2 vaccine booster dose in people living with HIV with severe immunosuppression [PDF]

, 2023
Anaïs Corma‐Gómez, Marta Fernández‐Fuertes, Laura Viñuela, Carmen Baxin Domínguez, Marta Santos, Ana Fuentes, Almudena Rojas, N.J. Fernández-Pérez, Jesica Martín Carmona, Esther Serrano‐Conde, Luís Miguel Real, Joaquín Mendoza, Juan Macı́as, Juan A. Pineda, Féderico García   +14 more
openalex   +1 more source

Neutralizing antibodies in convalescent patients [PDF]

Nature Reviews Immunology, 2020
Uhl, LFK, Chauveau, A
openaire   +3 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Patient-derived monoclonal antibody neutralizes HCV infection in vitro and vivo without generating escape mutants

, 2022
Hiroshi Yokokawa, Midori Shinohara, Yuji Teraoka, Michio Imamura, Noriko Nakamura, Noriyuki Watanabe, Tomoko Date, Hideki Aizaki, Tomokatsu Iwamura, Hideki Narumi, Kazuaki Chayama, Takaji Wakita   +11 more
openalex   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source