Results 171 to 180 of about 216,402 (213)

Neutralizing antibody in rodent malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1975
Small numbers of rat erythrocytes infected with viable P. berghei, when inoculated into susceptible rats together with hyperimmune rat serum (HIS), are fully neutralized. Serum from convalescent rats delays the onset of patency but does not neutralize. The neutralizing efficiency of HIS rises in proportion to the number of successive reinoculations of ...
J, Golenser, D T, Spira, A, Zuckerman
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Neutralizing antibody in nonallergic individuals

Journal of Allergy, 1952
Abstract Neutralizing antibody titrations were carried out in series of nonatopic human volunteers receiving one of the following ragweed preparations: (1) aqueous, (2) dialyzed aqueous, (3) alum precipitated, and (4) tannic acid precipitated extract. Also, extracts were made up to contain one of the following: (5) 10 per cent polyvinylpyrrolidone, (6)
S, MALKIEL, S M, FEINBERG
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Production of Neutralizing Antibody

Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa, Shuang, Liu
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Neutralizing Antibodies Against Calcitonin

Hormone and Metabolic Research, 1993
The use of calcitonin (CT) is established as a treatment of Paget's disease of bone and postmenopausal osteoporosis (PMO). Salmon calcitonin (sCT), which differs in 14 of the 32 amino acids from human calcitonin, has found a wider distribution world wide, although antibody formation against sCT has been reported in more than 70% of the patients on ...
A, Grauer, H H, Reinel, R, Ziegler, F, Raue   +3 more
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Statistical issues in neutralizing antibodies

Neurology, 2003
Frequently the question of the effects of neutralizing antibodies (NAbs) is stated, but not clearly. Some ask: “Are we sure NAbs are important?” And others ask: “Are we sure NAbs are NOT important?” These two questions can lead to different statistical designs and different approaches to the investigation of the impact of NAbs.
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Protective neutralizing antibodies

Science, 2020
Coronavirus Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Rogers et al.
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Perspectives on the neutralization of interferons by antibody

Neurology, 2003
Interferon (IFN) neutralizing antibody (NAb) interferes with the binding of the IFN molecule to its cellular receptor, thereby preventing receptor activation required to trigger the cascade of signal transduction events that lead to the varied actions of IFN.
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Testing for neutralizing antibodies

British Journal of Neuroscience Nursing, 2007
Interferon-beta drugs for multiple sclerosis sometimes give rise to immune proteins that neutralize their effects. Nicola O'Connell and Bronwen Roper look at testing for these neutralizing antibodies
Nicola O'Connell, Bronwen Roper
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Interferon-β antibodies have a higher affinity in patients with neutralizing antibodies compared to patients with non-neutralizing antibodies

Journal of Neuroimmunology, 2006
In this study, we investigated the affinity, determined by a relative affinity assay, using increasing concentrations of sodium-isothiocyanate to disrupt the antigen antibody binding of neutralizing and non-neutralizing antibodies against interferon-beta (IFNbeta)-1a and -1b in 73 serum samples of MS patients treated with IFNbeta-1a or -1b.
C, Gneiss, P, Tripp, R, Ehling, M, Khalil, A, Lutterotti, R, Egg, I, Mayringer, B, Künz, T, Berger, M, Reindl, F, Deisenhammer   +10 more
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Antibody neutralization and escape by HIV-1

Nature, 2003
Neutralizing antibodies (Nab) are a principal component of an effective human immune response to many pathogens, yet their role in HIV-1 infection is unclear. To gain a better understanding of this role, we examined plasma from patients with acute HIV infection.
Xiping, Wei, Julie M, Decker, Shuyi, Wang, Huxiong, Hui, John C, Kappes, Xiaoyun, Wu, Jesus F, Salazar-Gonzalez, Maria G, Salazar, J Michael, Kilby, Michael S, Saag, Natalia L, Komarova, Martin A, Nowak, Beatrice H, Hahn, Peter D, Kwong, George M, Shaw   +14 more
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