Results 161 to 170 of about 216,402 (213)

Potent Cross-neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein. [PDF]

Adv Sci (Weinh)
Ren Y, Fan P, Zhang X, Fang T, Chen Z, Yao Y, Chi X, Zhang G, Zhao X, Sun B, Li F, Liu Z, Song Z, Zhang B, Peng C, Li E, Yang Y, Li J, Chiu S, Yu C.   +19 more
europepmc   +1 more source

Screening of Neutralizing Antibodies Targeting Gc Protein of RVFV. [PDF]

Viruses
Zhao C, Hao M, Bian T, Zhao X, Chi X, Chen Z, Fu G, Zhu Z, Fang T, Yu C, Li J, Chen W.   +11 more
europepmc   +1 more source

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Broadly Neutralizing Antiviral Antibodies

Annual Review of Immunology, 2013
A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive immune response. The widely held view has been that the great variability of viral glycoproteins would be an absolute obstacle to the development of antibody-based therapies or vaccines that could confer broad and long-lasting protection.
Corti D., Lanzavecchia A.
openaire   +3 more sources

Production of Neutralizing Antibody

2018
Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa, Shuang, Liu, Hitoshi, Hasegawa   +2 more
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Neutralization of HIV by Antibodies

2008
Antibodies can neutralize HIV-1 with potency and cross-reactivity that varies widely and is related but not correlated to their antigen-binding affinity. Therefore, in addition to measuring binding affinity, an evaluation of the antibody neutralizing activity in tissue cultures is important for development of antibody-based therapeutics, design of ...
Ilia, Prado, Timothy R, Fouts, Antony S, Dimitrov   +2 more
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The secretion of virus-neutralizing antibodies

Archiv f�r die gesamte Virusforschung, 1967
Considerable evidence supports the concept that the immune defense against infectious agents that attack primarily the cells of the mucosal linings lies in secreted antibodies belonging to the IgA class of immunoglobulins. The problem that thus arises, in connection with the possible use of adjuvants in active immunization against these infectious ...
A, Giovanardi, A, Albano, L, Amante, S, De Donato, B, Pernis   +4 more
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Antibody Neutralization in Hypoprothrombinaemic Plasma

Pathophysiology of Haemostasis and Thrombosis, 2009
The technique of antibody neutralization has been used to study the plasma of a large group of patients with hypoprothrombinaemia of diverse causes. The associated disorders included obstructive jaundice, acute infective hepatitis and chronic parenchymal liver disease. A number of patients were receiving warfarin and salicylate therapy. Irrespective of
J D, Parkin, F, Madaras, P A, Castaldi
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Neutralizing antibodies and antigens in AIDS

Infection, 1991
Until recently, much of the effort put into development of an AIDS vaccine has focussed on the elicitation of a neutralizing antibody response. The viral target of neutralization, HIV envelope glycoprotein, has been produced in bulk through recombinant techniques, but has had little success as a vaccine.
S G, Norley, R, Kurth
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Neutralizing antibodies to interferon

Neurology, 2007
The impact of neutralizing antibodies (NAbs) to interferon-beta (IFN-beta) on clinical and imaging parameters in multiple sclerosis (MS) is reviewed. An effect on relapse rates and imaging parameters was noted in patients who tested positive for NAbs, but disability measures were unaffected or showed a trend toward improvement.
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Neutralization of Arenaviruses by Antibody

1987
Neutralization of infectivity is the end result of a number of alternative or synergistic reactions between a virus and antibody directed against certain antigenic determinants on its surface. These reactions prevent either the attachment of virus to a particular host cell by steric hindrance, the entry of virus into the cell, or the uncoating of the ...
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