Results 141 to 150 of about 309,985 (359)

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

, 2020
James Brett Case, Paul W. Rothlauf, Rita E. Chen, Zhuoming Liu, Haiyan Zhao, Arthur S. Kim, Louis-Marie Bloyet, Qiru Zeng, Stephen Tahan, Lindsay Droit, Ma. Xenia G. Ilagan, Michael A. Tartell, Gaya K. Amarasinghe, Jeffrey P. Henderson, Shane Miersch, Mart Ustav, Sachdev S. Sidhu, Herbert W. Virgin, David Wang, Siyuan Ding, Davide Corti, Elitza S. Theel, Daved H. Fremont, Michael Diamond, Sean P. J. Whelan   +24 more
openalex   +1 more source

Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection [PDF]

, 2019
Yanling Wu, Jing Xue, Chunyu Wang, Wei Li, Lili Wang, Weizao Chen, Ponraj Prabakaran, Desheng Kong, Yujia Jin, Dan Hu, Yulu Wang, Lei Cheng, Diao Yu, Chao Tu, Ariola Bardhi, Igor A. Sidorov, Liying Ma, Harris Goldstein, Chuan Qin, Lu Lu, Shibo Jiang, Dimiter S. Dimitrov, Tianlei Ying   +22 more
openalex   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Performance evaluation of four kits for the detection of neutralizing antibody against SARS-CoV-2 in human serum

Journal of Clinical Virology Plus
To evaluate four novel SARS-CoV-2 neutralizing antibody assay kits' application in neutralizing antibodies of population. Questionnaires from the voluntary participating researchers and selected the qualified questionnaires to analyse.
Hui Zhen, Ya Cheng, Qimeng Sun, Ying Zheng, Lili Tian, Chao Shen, Li Li, Jie Gong, Yonggang Chen, Hongping Ba   +9 more
doaj   +1 more source

Additional file 4 of Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants

, 2021
Chunyan Yi, Xiaoyu Sun, Yixiao Lin, Chenjian Gu, Longfei Ding, Xiao Lu, Zhuo Yang, Yaguang Zhang, Liyan Ma, Wangpeng Gu, Aidong Qu, Xu Zhou, Xiuling Li, Jianqing Xu, Zhiyang Ling, Youhua Xie, Hongzhou Lu, Bing Sun   +17 more
openalex   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Function and structure of broadly neutralizing antibodies against SARS-CoV-2 Omicron variants isolated from prototype strain infected convalescents

Journal of Translational Medicine
Background The ongoing emergence of evolving SARS-CoV-2 variants poses great threaten to the efficacy of authorized monoclonal antibody-based passive immunization or treatments. Developing potent broadly neutralizing antibodies (bNabs) against SARS-CoV-2
Dan Li, Caiqin Hu, Junwei Su, Shuo Du, Ying Zhang, Wanqi Ni, Li Ren, Yanling Hao, Yi Feng, Changzhong Jin, Shuo Wang, Xinxian Dai, Zheng Wang, Biao Zhu, Junyu Xiao, Yiming Shao   +15 more
doaj   +1 more source

A Nonneutralizing Anti-HIV-1 Antibody Turns into a Neutralizing Antibody When Expressed on the Surface of HIV-1-Susceptible Cells: A New Way to Fight HIV [PDF]

, 2004
Seung‐Jae Lee, Laura Garza, Jun Yao, Abner Louis Notkins, Paul Zhou   +4 more
openalex   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

COVID‐19: are neutralizing antibodies neutralizing enough? [PDF]

Transfusion, 2020
openaire   +2 more sources