Results 281 to 290 of about 207,642 (318)

Perspectives on the neutralization of interferons by antibody

Neurology, 2003
Interferon (IFN) neutralizing antibody (NAb) interferes with the binding of the IFN molecule to its cellular receptor, thereby preventing receptor activation required to trigger the cascade of signal transduction events that lead to the varied actions of IFN.
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Testing for neutralizing antibodies

British Journal of Neuroscience Nursing, 2007
Interferon-beta drugs for multiple sclerosis sometimes give rise to immune proteins that neutralize their effects. Nicola O'Connell and Bronwen Roper look at testing for these neutralizing antibodies
Nicola O'Connell, Bronwen Roper
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Interferon-β antibodies have a higher affinity in patients with neutralizing antibodies compared to patients with non-neutralizing antibodies

Journal of Neuroimmunology, 2006
In this study, we investigated the affinity, determined by a relative affinity assay, using increasing concentrations of sodium-isothiocyanate to disrupt the antigen antibody binding of neutralizing and non-neutralizing antibodies against interferon-beta (IFNbeta)-1a and -1b in 73 serum samples of MS patients treated with IFNbeta-1a or -1b.
C, Gneiss, P, Tripp, R, Ehling, M, Khalil, A, Lutterotti, R, Egg, I, Mayringer, B, Künz, T, Berger, M, Reindl, F, Deisenhammer   +10 more
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Antibody neutralization and escape by HIV-1

Nature, 2003
Neutralizing antibodies (Nab) are a principal component of an effective human immune response to many pathogens, yet their role in HIV-1 infection is unclear. To gain a better understanding of this role, we examined plasma from patients with acute HIV infection.
Xiping, Wei, Julie M, Decker, Shuyi, Wang, Huxiong, Hui, John C, Kappes, Xiaoyun, Wu, Jesus F, Salazar-Gonzalez, Maria G, Salazar, J Michael, Kilby, Michael S, Saag, Natalia L, Komarova, Martin A, Nowak, Beatrice H, Hahn, Peter D, Kwong, George M, Shaw   +14 more
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The influence of complement on cytomegalovirus neutralization by antibodies

Archiv f�r die gesamte Virusforschung, 1972
The influence of complement on the neutralization of cytomegalovirus by antibodies has been studied using human sera and antisera prepared in rabbits with various strains of cytomegalovirus (Ad 169, C 87, Davis andT 27). Examination of patient sera showed that addition of 2 per cent complement had only a weak and non-significant enhancing effect on ...
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Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans

Cell Host and Microbe, 2021
Kanika Vanshylla, Veronica Di Cristanziano, Felix Dewald   +2 more
exaly  

Neutralization by Fragments of Antibody

1993
Experiments to determine whether or not the whole antibody molecule is necessary for neutralization were made possible by digestion with the proteolytic enzymes pepsin, which releases the Fc region leaving an F(ab)2 structure, or papain, which results in a monovalent antigen-binding fragment (Fab). Most data relate to IgG.
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Neutralization of interferon by specific antibody

Virology, 1962
K, PAUCKER, K, CANTELL
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Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins

Immunity, 2021
Netanel Tzarum, Xiaohe Lin, Erick Giang   +2 more
exaly  

Zika-neutralizing antibodies

Nature Immunology, 2017
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