Results 71 to 80 of about 416,964 (269)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

β-Hydroxybutyrate inhibits the spontaneous apoptosis of neutrophils through a degranulation–macrophage-1 antigen axis in cows with subclinical ketosis

Journal of Dairy Science
: Subclinical ketosis (SCK), a common metabolic disorder in dairy cows during the peripartum period, is accompanied by systemic inflammation and elevated circulating BHB.
Kexin Wang, Guowen Liu, Ke Zhang, Zhiyong Li, Yan Ren, Shang Jiang, Xiliang Du, Lin Lei, Wenwen Gao, Zhe Wang, Xinwei Li, Yuxiang Song   +11 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Regenerative potential of immune cells after traumatic muscle injury

Frontiers in Immunology
Traumatic muscle injury (TMI) causes significant morbidity and socioeconomic burden. Immune cells are central to the subsequent regenerative response, orchestrating dynamic interactions between innate and adaptive immunity.
Su Pu, Guangmin Hu, Yulu Cao, Guoming Shen, Yuqing Wang   +4 more
doaj   +1 more source

Dynamic ROS Production and Gene Expression of Heifers Blood Neutrophil in a Oligofructose Overload Model

Frontiers in Veterinary Science, 2020
Alimentary oligofructose (OF) overload can induce several diseases in cattle, such as ruminal acidosis, laminitis, and synovitis. The role of blood polymorphonuclear neutrophil (PMN) remains unclear during OF overload.
Shuaichen Li, Shuaichen Li, Jiafeng Ding, Jiafeng Ding, Lihong Jiang, Lihong Jiang, Muhammad Abid Hayat, Muhammad Abid Hayat, Qiaozhi Song, Qiaozhi Song, Yuepeng Li, Yuepeng Li, Xianhao Zhang, Xianhao Zhang, Jiantao Zhang, Jiantao Zhang   +15 more
doaj   +1 more source

Heterogeneity of neutrophils

Nature Reviews Immunology, 2019
Structured models of ontogenic, phenotypic and functional diversity have been instrumental for a renewed understanding of the biology of immune cells, such as macrophages and lymphoid cells. However, there are no established models that can be used to define the diversity of neutrophils, the most abundant myeloid cells.
Lai Guan Ng, Renato Ostuni, Andrés Hidalgo   +2 more
openaire   +3 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Mitochondrial ROS–ER Stress Axis Governs IL-10 Production in Neutrophils and Regulates Inflammation in Murine Chlamydia pneumoniae Lung Infection

Cells
Neutrophils are among the first cells to be recruited to the lungs during Chlamydia pneumoniae infection in mouse models; however, their regulatory functions are not yet fully understood.
Bin Chou, Kazunari Ishii, Yusuke Kurihara, Akinori Shimizu, Michinobu Yoshimura, Ryo Ozuru, Ryota Itoh, Atsuhiko Sakamoto, Kenji Hiromatsu   +8 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Cell Surface Parameters for Accessing Neutrophil Activation Level with Atomic Force Microscopy

Cells
In this study, we examine the topography and adhesion images of the cell surface of neutrophils during the activation process. Our analysis of cell surface parameters indicates that the most significant changes in neutrophils occur within the first 30 ...
Oksana M. Tilinova, Vladimir Inozemtsev, Ekaterina Sherstyukova, Snezhanna Kandrashina, Mikhail Pisarev, Andrey Grechko, Nina Vorobjeva, Viktoria Sergunova, Maxim E. Dokukin   +8 more
doaj   +1 more source