Results 91 to 100 of about 152,807 (272)
Proceedings of the Shevchenko Scientific Society: Medical Sciences, 2019 Introduction. Neutrophils play an important role in the innate immune response. While patrolling the body, they find pathogens and destroy them by means of phagocytosis, degranulation, or formation of neutrophil extracellular traps (NETs).
T. Dumych, S. Paryzhak, R. Bilyy
doaj +1 more source
Emphysema in an 11‐month‐old boy with alpha‐1 antitrypsin deficiency
Pediatric Investigation, EarlyView.Pediatric development of emphysema in Alpha‐1 Antitrypsin Deficiency (A1ATD) has been rarely described. In this case report, we document an 11‐month boy with A1ATD phenotype PiZZ with basilar centrilobular emphysema, the earliest such documented case.
Irvin Yi +3 more
wiley +1 more source
, 2017 Human neutrophil elastase (HNE) is an important N-glycosylated serine protease in the innate immune system, but the structure and immune-modulating functions of HNE N-glycosylation remain undescribed.
Ole Østergaard +9 more
core +1 more source
, 2022 Chronic obstructive pulmonary disease (COPD) along with asthma is a major and increasing global health problem. Smoking contributes to about 80%–90% of total COPD cases in the world.
Ulaganathan Mabalirajan (408250) +8 more
core +1 more source
Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events
Phytotherapy Research, EarlyView.An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia +1 more
wiley +1 more source
Biomarkers to predict outcomes in diabetic foot ulcers
VIEW, EarlyView.Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro +6 more
wiley +1 more source
Inflammatory mediators, infection, sepsis, and multiorgan failure after severe trauma [PDF]
, 1992 The relation of (multiple) organ failure (OF) to the release of inflammatory mediators and the incidence of infection and sepsis was studied prospectively in 100 patients with multiple trauma (injury severity score=37).
Waydhas, Christian +7 more
core +1 more source
BMC Pulmonary Medicine, 2018 Background Cystic fibrosis (CF) is associated with bacterial pulmonary infections and neutrophil-dominated inflammation in the airways. The aim of this study was to evaluate the neutrophil-derived protein Heparin-binding protein (HBP) as a potential ...
Gisela Hovold +4 more
doaj +1 more source
Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep [PDF]
, 2006 Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large-animal model of emphysema using repeated LPS administration into sheep lung segments.
Blundell, Richard +8 more
core +1 more source
Allergy, EarlyView.ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source