Results 161 to 170 of about 57,341 (275)

Elastase-alpha1-proteinase inhibitor complex [PDF]

, 1984
Bergmeyer, H. U., Bergmeyer, J., Graßl, M., Jochum, Marianne, Neumann, S.   +4 more
core   +1 more source

Endothelium‐Treg Communication Through Extracellular Vesicle Transfer Exacerbates Acute Respiratory Distress Syndrome

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Here, we reveal that pulmonary endothelium‐derived EVs aggravate lung inflammation via destabilizing Tregs during ALI/ARDS. Mechanistically, Tregs absorbs EV‐Med1, which promotes the secretion of IL‐21. This cytokine in turn induces hyper‐phosphorylation of STAT3 in Tregs thus induing loss of Foxp3, creating an hyperinflammatory ALI/ARDS ...
Xu Liu, Wei Huang, Xiwen Zhang, Shiming Li, Haofei Wang, Zongsheng Wu, Shuangfeng Zi, Lu Wang, Ling Liu, Yi Yang, Jianfeng Xie, Mingzhu Zheng, Jie Chao, Haibo Qiu   +13 more
wiley   +1 more source

Neutrophil elastase promotes mucin secretion in airway epithelial cells through the MARCKS/ACK1/cortactin pathway. [PDF]

Cent Eur J Immunol
He M, Li Q, Ouyang S, Liu Y, Perelman JM, Kolosov VP, Zhou X, Li Y.   +7 more
europepmc   +1 more source

Neutrophil Elastase and Trastuzumab Responsiveness [PDF]

Oncology Research and Treatment, 2007
Michiko Harao, Takashi Sato, Takashi Fukutomi, Kyoko Yorozuya, Miyuki Takasugi, Yukako Mohri, Takao Mizumoto, Satoshi Takahashi, Jun-ichi Yamashita   +8 more
openaire   +1 more source

Increased Risk of Cholesteatoma in Individuals With Alpha‐1 Antitrypsin Deficiency: A Cohort Study

The Laryngoscope, Volume 136, Issue 2, Page 955-960, February 2026.
Patients with AATD had a 3.6‐fold increased risk of cholesteatoma surgery (HR: 3.62) compared to controls. These findings suggest that AATD may contribute to the development of cholesteatoma. ABSTRACT Objective To estimate the risk of cholesteatoma in patients with alpha‐1 antitrypsin deficiency (AATD) compared to the general population using time‐to ...
Abdulla Ali, Helene Andresen Ravn, Morten Dahl, Bjarki Ditlev Djurhuus   +3 more
wiley   +1 more source

Neutrophil elastase promotes low molecular weight cyclin E1 formation to accelerate osteosarcoma proliferation. [PDF]

Front Immunol
Xu J, Shi Q, Zeng F, Ren T, Wei R, Tang X.   +5 more
europepmc   +1 more source

Feasibility study of very high aprotinin dosage in polytrauma patients [PDF]

, 1987
Clasen, C., Jochum, Marianne, Müller-Esterl, Werner, Redl, H., Schlag, G.   +4 more
core  

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Mechanochemical Synthesis of X‐Vinylbenziodoxol(on)es and One‐Pot Conversion to Complex Alkenes**

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
The synthesis of a wide range of complex 1,2‐di(heteroatom)‐substituted (Z)‐alkenes is achieved through a mechanochemical one‐pot reaction of ethynylbenziodoxol(on)es (EBX/EBO) with a variety of heteroatom nucleophiles. The mechanochemical activation enables synthesis of a range of novel vinylbenziodoxol(on)es (VBX/VBO) whose synthesis is inefficient ...
Sayad Doobary, Judith Braunreuther, Andrew K. Inge, Berit Olofsson   +3 more
wiley   +2 more sources

Neutrophils Induce P-Selectin Shedding from Activated Platelets Via Neutrophil Elastase. [PDF]

Inflammation
Huang Y, Ling L, He S, Liu C, Huang X, Wang S, Yu Z, Zhou J.   +7 more
europepmc   +1 more source