Results 11 to 20 of about 2,916 (168)

Neutrophil Extracellular Traps in Periodontitis

Cells, 2020
Neutrophils are key cells of the immune system and have a decisive role in fighting foreign pathogens in infectious diseases. Neutrophil extracellular traps (NETs) consist of a mesh of DNA enclosing antimicrobial peptides and histones that are released ...
Antonio Magán-Fernández, Sarmad Muayad Rasheed Al-Bakri, Francisco O’Valle, Cristina Benavides-Reyes, Francisco Abadía-Molina, Francisco Mesa   +5 more
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Neutrophil Extracellular Traps, Angiogenesis and Cancer

Biomedicines, 2022
Human neutrophils, the most abundant circulating leukocytes, are fundamental components of the host response against different pathogens. Until a few years ago, neutrophils received limited attention in cancer immunology. Recently, it was discovered that
Remo Poto, Leonardo Cristinziano, Luca Modestino, Amato de Paulis, Gianni Marone, Stefania Loffredo, Maria Rosaria Galdiero, Gilda Varricchi   +7 more
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Neutrophil activation and neutrophil derived neutrophil extracellular trap formation in patients with coronary artery ectasia

BMC Cardiovascular Disorders, 2020
Background This study investigated neutrophil activation and neutrophil-derived extracellular traps formation in coronary artery ectasia. Methods We enrolled 90 patients who underwent coronary angiography, and included 30 patients with coronary artery ...
Yuchao Guo, Ruifeng Liu, Lianfeng Chen, Wei Wu, Shuyang Zhang   +4 more
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Propagation of thrombosis by neutrophils and extracellular nucleosome networks

Haematologica, 2017
Neutrophils, early mediators of the innate immune defense, are recruited to developing thrombi in different types of thrombosis. They amplify intravascular coagulation by stimulating the tissue factor-dependent extrinsic pathway via inactivation of ...
Susanne Pfeiler, Konstantin Stark, Steffen Massberg, Bernd Engelmann   +3 more
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Neutrophil extracellular traps go viral

Frontiers in Immunology, 2016
Neutrophils are the most numerous immune cells. Their importance as a first line of defense against bacterial and fungal pathogens is well described. In contrast, the role of neutrophils in controlling viral infections is less clear. Bacterial and fungal
Günther Schönrich, Martin J Raftery
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Neutrophil Extracellular Traps and Neutrophil-Derived Extracellular Vesicles: Common Players in Neutrophil Effector Functions

Diagnostics, 2022
Neutrophil granulocytes are a central component of the innate immune system. In recent years, they have gained considerable attention due to newly discovered biological effector functions and their involvement in various pathological conditions.
Heiko Pfister
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Evolution of neutrophil extracellular traps in the pathology of stroke

Neural Regeneration Research
Stroke is a major cause of death and disability worldwide, and its pathogenesis is complex, involving multiple pathological processes, such as thrombosis, ischemia-reperfusion injury, inflammatory response, and blood–brain barrier disruption.
Wenjing Ning, Qian Wang, Yuzhen Xu
doaj   +1 more source

Neutrophil Extracellular Traps and Microcrystals

Journal of Immunology Research, 2017
Neutrophil extracellular traps represent a fascinating mechanism by which PMNs entrap extracellular microbes. The primary purpose of this innate immune mechanism is thought to localize the infection at an early stage.
Balázs Rada
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Neutrophil Extracellular Traps Formation and Aggregation Orchestrate Induction and Resolution of Sterile Crystal-Mediated Inflammation

Frontiers in Immunology, 2018
The formation of neutrophil extracellular traps (NETs) to immobilize pathogens represents a novel antimicrobial strategy of the immune system. The microcrystals related to human diseases are classified into endogenous microcrystals, including monosodium ...
Yanhong Li, Xue Cao, Yi Liu, Yi Zhao, Yi Zhao, Martin Herrmann   +5 more
doaj   +1 more source

Stroke-derived neutrophils demonstrate higher formation potential and impaired resolution of CD66b + driven neutrophil extracellular traps

BMC Neurology, 2022
Background Recent evidence suggests a merging role of immunothrombosis in the formation of arterial thrombosis. Our study aims to investigate its relevance in stroke patients. Methods We compared the peripheral immunological profile of stroke patients vs.
Angeliki Datsi, Laura Piotrowski, Markella Markou, Thomas Köster, Isabelle Kohtz, Kerstin Lang, Sabine Plöttner, Heiko Udo Käfferlein, Burkhard Pleger, Ramon Martinez, Bogdan Pintea, Roland Fried, Marcus Müller, Rene Chapot, Konstantinos Gousias   +14 more
doaj   +1 more source