Results 31 to 40 of about 689,523 (253)

Neutrophil Extracellular Traps Formation and Aggregation Orchestrate Induction and Resolution of Sterile Crystal-Mediated Inflammation

Frontiers in Immunology, 2018
The formation of neutrophil extracellular traps (NETs) to immobilize pathogens represents a novel antimicrobial strategy of the immune system. The microcrystals related to human diseases are classified into endogenous microcrystals, including monosodium ...
Yanhong Li, Xue Cao, Yi Liu, Yi Zhao, Yi Zhao, Martin Herrmann   +5 more
doaj   +1 more source

Neutrophil extracellular traps mediate neuro-immunothrombosis

Neural Regeneration Research
Neutrophil extracellular traps are primarily composed of DNA and histones and are released by neutrophils to promote inflammation and thrombosis when stimulated by various inflammatory reactions.
Jianbo Lou, Jianning Zhang, Quanjun Deng, Xin Chen   +3 more
doaj   +1 more source

Stroke-derived neutrophils demonstrate higher formation potential and impaired resolution of CD66b + driven neutrophil extracellular traps

BMC Neurology, 2022
Background Recent evidence suggests a merging role of immunothrombosis in the formation of arterial thrombosis. Our study aims to investigate its relevance in stroke patients. Methods We compared the peripheral immunological profile of stroke patients vs.
Angeliki Datsi, Laura Piotrowski, Markella Markou, Thomas Köster, Isabelle Kohtz, Kerstin Lang, Sabine Plöttner, Heiko Udo Käfferlein, Burkhard Pleger, Ramon Martinez, Bogdan Pintea, Roland Fried, Marcus Müller, Rene Chapot, Konstantinos Gousias   +14 more
doaj   +1 more source

Neutrophil Extracellular Traps Participate in Cardiovascular Diseases: Recent Experimental and Clinical Insights. [PDF]

, 2020
Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or dying neutrophils, decorated with various protein mediators, become solid-state
Libby, Peter, Soehnlein, O, Soehnlein, Oliver, Döring, Yvonne, Döring, Y, Libby, P   +5 more
core   +1 more source

Neutrophil extracellular traps: from physiology to pathology( ) [PDF]

, 2021
At the frontline of the host defence response, neutrophil antimicrobial functions have adapted to combat infections and injuries of different origins and magnitude.
Hidalgo, Andres, Libby, Peter, Silvestre-Roig, Carlos, Soehnlein, O, Aramburu, Iker Valle, Soehnlein, Oliver, Hidalgo, A, Aramburu, IV, Silvestre-Roig, C, Papayannopoulos, Venizelos, Libby, P, Papayannopoulos, V   +11 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Ginsenoside Rb1 ameliorates neutrophil extracellular traps-induced vascular endothelial damage by suppressing apoptosis

Bangladesh Journal of Pharmacology
The study aims to investigate the effect of ginsenoside Rb1 on improving neutrophil extracellular traps-induced vascular endothelial damage. The CCK8 assay was used to evaluate the impact of ginsenoside Rb1 on cell activity.
Biao Zhang, Junkai Zhao, Jiamin Yin, Jiaping Chen, Lingqi Xu   +4 more
doaj   +1 more source

Netosis in the pathogenesis of antiphospholipid syndrome and systemic lupus erythematosus

Современная ревматология, 2021
Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases. In recent years, APS has been considered as an autoimmune thrombo-inflammatory disease.
K. S. Nurbaeva, T. M. Reshetnyak, A. M. Lila   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Neutrophil extracellular traps in acute coronary syndrome

Journal of Inflammation, 2023
Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart failure, arrhythmia and even sudden death. It is the major cause of disability and death worldwide.
Yawen Wu, Shilin Wei, Xiangyang Wu, Yongnan Li, Xue Han   +4 more
doaj   +1 more source