Results 21 to 30 of about 75,140 (320)

How Neutrophil Extracellular Traps Become Visible [PDF]

Journal of Immunology Research, 2016
Neutrophil extracellular traps (NETs) have been identified as a fundamental innate immune defense mechanism against different pathogens. NETs are characterized as released nuclear DNA associated with histones and granule proteins, which form an ...
Nicole de Buhr, Maren von Köckritz-Blickwede   +1 more
doaj   +3 more sources

Neutrophil extracellular traps characterize caseating granulomas

Cell Death and Disease
Tuberculosis (TB) remains one of the top 10 causes of death worldwide and still poses a serious challenge to public health. Recent attention to neutrophils has uncovered unexplored areas demanding further investigation.
Leticija Zlatar, Jasmin Knopf, Jeeshan Singh, Han Wang, Marco Muñoz-Becerra, Irmgard Herrmann, Rebecca C. Chukwuanukwu, Markus Eckstein, Philip Eichhorn, Ralf J. Rieker, Elisabeth Naschberger, Andreas Burkovski, Veit Krenn, Rostyslav Bilyy, Tetiana Butova, Iryna Liskina, Ihor Kalabukha, Oleg Khmel, Michael Boettcher, Georg Schett, Dmytro Butov, Anton Tkachenko, Martin Herrmann   +22 more
doaj   +4 more sources

Neutrophil extracellular traps impair regeneration [PDF]

Journal of Cellular and Molecular Medicine, 2021
Abstract Fibrosis is a major health burden across diseases and organs. To remedy this, we study wound‐induced hair follicle neogenesis (WIHN) as a model of non‐fibrotic healing that recapitulates embryogenesis for de novo hair follicle morphogenesis after wounding.
Eric Wier, Mayumi Asada, Gaofeng Wang, Martin P. Alphonse, Ang Li, Chase Hintelmann, Evan Sweren, Christine Youn, Brittany Pielstick, Roger Ortines, Chenyi Lyu, Maria Daskam, Lloyd S. Miller, Nathan K. Archer, Luis A. Garza   +14 more
openaire   +2 more sources

Neutrophil extracellular traps [PDF]

Current Biology, 2011
What are neutrophil extracellular traps, or NETs? Neutrophils, the most abundant immune cells in humans, are the first line of defense against invading pathogens. They employ a wide array of anti-microbial strategies, most notably phagocytosis, to attack and eliminate pathogens.
Amulic, Borko, Hayes, Garret
openaire   +4 more sources

Phagocytosis and neutrophil extracellular traps [PDF]

Faculty Reviews, 2020
Neutrophils are recruited rapidly to sites of infection in response to host- and/or microbe-derived proinflammatory molecules. At such sites, neutrophils phagocytose microbes and are activated to produce superoxide and other reactive oxygen species (ROS). In addition, neutrophils contain stores of antimicrobial peptides and enzymes that work in concert
DeLeo, Frank R, Allen, Lee-Ann H
openaire   +2 more sources

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

Journal of Experimental Medicine, 2020
In this Perspective, autopsy results and literature are presented supporting the hypothesis that neutrophil extracellular traps (NETs) may contribute to organ damage and mortality in COVID-19.
B. Barnes, J. M. Adrover, Amelia Baxter-Stoltzfus, A. Borczuk, J. Cools-Lartigue, J. M. Crawford, J. Daßler-Plenker, P. Guerci, C. Huynh, J. Knight, M. Loda, M. Looney, F. McAllister, R. Rayes, S. Renaud, S. Rousseau, S. Salvatore, R. Schwartz, J. Spicer, C. C. Yost, Andrew Weber, Y. Zuo, M. Egeblad   +22 more
semanticscholar   +1 more source

Neutrophil Extracellular Traps are Present in Immune-complex-mediated Cutaneous Small Vessel Vasculitis and Correlate with the Production of Reactive Oxygen Species and the Severity of Vessel Damage

Acta Dermato-Venereologica, 2020
Formation of neutrophil extracellular traps has been implicated in autoimmunity. However, the presence and clinical relevance of neutrophil extracellular traps in immune-complex-mediated cutaneous small and medium vessel vasculitides has not been ...
Christina Bergqvist, Rémi Safi, George El Hasbani, Ossama Abbas, Abdulghani Kibbi, Dany Nassar   +5 more
doaj   +1 more source

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

Blood, 2020
COVID-19 affects millions of patients worldwide, with clinical presentation ranging from isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator support.
E. Middleton, Xue-Yan He, F. Denorme, Robert A. Campbell, David Ng, S. Salvatore, Maria Mostyka, Amelia Baxter-Stoltzfus, A. Borczuk, M. Loda, M. Cody, B. Manne, Irina Portier, Estelle M. Harris, Aaron C Petrey, E. Beswick, Aleah F. Caulin, A. Iovino, Lisa M. Abegglen, A. Weyrich, M. Rondina, M. Egeblad, J. Schiffman, C. C. Yost   +23 more
semanticscholar   +1 more source

Does postoperative inflammation or sepsis generate neutrophil extracellular traps that influence colorectal cancer progression? A systematic review

Surgery Open Science, 2020
Background: Colorectal cancer is the third most common cancer worldwide. Almost half of those that have a potentially curative resection go on to develop metastatic disease.
Georgia M. Carroll, BMed, PGDip, Grace L. Burns, BBiomed, Sci (Hons), Joel A. Petit, BSc, MBBS, MMed, Marjorie M. Walker, BMBS, FRCPA, Andrea Mathe, PhD, Stephen R. Smith, MBBS, BSc, FRACS, MS, PhD, Simon Keely, PhD, Peter G. Pockney, DM, MBBS, BSc, FRCS, FRACS   +7 more
doaj   +1 more source

Neutrophil Extracellular Trap-Driven Occlusive Diseases [PDF]

Cells, 2021
The enlightenment of the formation of neutrophil extracellular traps (NETs) as a part of the innate immune system shed new insights into the pathologies of various diseases. The initial idea that NETs are a pivotal defense structure was gradually amended due to several deleterious effects in consecutive investigations.
Kursat Oguz Yaykasli, Christine Schauer, Luis E. Muñoz, Aparna Mahajan, Jasmin Knopf, Georg Schett, Martin Herrmann   +6 more
openaire   +3 more sources