Results 31 to 40 of about 75,140 (320)

Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]

, 2017
NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina, D'Atri, Lina Paola, Fandiño, María Eugenia, Fondevila, Carlos, Guzman, María Alejandra, Kaufman, Tomás, Magosevich, Débora, Moreno, María Carolina, Schattner, Mirta Ana   +8 more
core   +1 more source

Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis

Journal of Experimental Medicine, 2023
Neutrophil extracellular traps and extracellular histones potentiate Th17 inflammation and bone destruction in animal models of periodontitis. Findings in patients with periodontitis provide human relevance and support further exploration of NET-mediated
Tae Sung Kim, L. M. Silva, V. Theofilou, T. Greenwell-Wild, Lu Li, D. Williams, Tomoko Ikeuchi, L. Brenchley, T. Bugge, P. Diaz, M. Kaplan, C. Carmona-Rivera, N. Moutsopoulos   +12 more
semanticscholar   +1 more source

Nucleosomes and neutrophil activation in sickle cell disease painful crisis

Haematologica, 2013
Activated polymorphonuclear neutrophils play an important role in the pathogenesis of vaso-occlusive painful sickle cell crisis. Upon activation, polymorphonuclear neutrophils can form neutrophil extracellular traps.
Marein Schimmel, Erfan Nur, Bart J. Biemond, Gerard J. van Mierlo, Shabnam Solati, Dees P. Brandjes, Hans-Martin Otten, John-John Schnog, Sacha Zeerleder   +8 more
doaj   +1 more source

Earthworm coelomocyte extracellular traps : structural and functional similarities with neutrophil NETs [PDF]

, 2018
ROD UJ /
Joanna Homa
core   +2 more sources

Triptolide inhibits neutrophil extracellular trap formation [PDF]

Annals of Translational Medicine, 2021
Triptolide (PG490), as a triterpene dicyclic oxide has been reported to increase the generation of reactive oxygen species (ROS) and nitric oxide (NO) and induce apoptosis of RAW 264.7 cells in a dose-dependent manner. The activity of death NETs plays an important role in anti-bacterial processes in the human body.
Guan, Haiyu, Xie, Lifen, Ji, Zhenzhen, Song, Rui, Qi, Jieying, Nie, Xiaoli   +5 more
openaire   +2 more sources

Gastropod-derived haemocyte extracellular traps entrap metastrongyloid larval stages of Angiostrongylus vasorum, Aelurostrongylus abstrusus and Troglostrongylus brevior [PDF]

, 2017
Background: Phagocyte-derived extracellular traps (ETs) were recently demonstrated mainly in vertebrate hosts as an important effector mechanism against invading parasites.
Gärtner, Ulrich, Hermosilla, Carlos, Lange, Malin K., Mejer, Helena, Muñoz-Caro, Tamara, Penagos-Tabares, Felipe, Schaper, Roland, Taubert, Anja   +7 more
core   +4 more sources

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

Journal of Experimental Medicine, 2020
The knowledge of COVID-19 pathophysiology is pivotal for the discovery of effective treatments. Here, we described that SARS-CoV-2 triggers the release of ACE2-depended neutrophil extracellular traps (NETs) that mediate lung pathology, supporting the use
F. Veras, M. Pontelli, C. Silva, J. Toller-Kawahisa, M. D. de Lima, D. Nascimento, A. Schneider, Diego B. Caetité, L. Tavares, I. Paiva, R. Rosales, David F. Colon, R. Martins, I. Castro, G. Almeida, M. I. Lopes, M. Benatti, L. Bonjorno, M. Giannini, R. Luppino-Assad, S. L. Almeida, F. Vilar, R. Santana, V. Bollela, M. Auxiliadora-Martins, M. Borges, C. H. Miranda, A. Pazin-Filho, L. L. D. da Silva, L. D. Cunha, D. Zamboni, F. Dal-Pizzol, L. O. Leiria, Siyuan Li, S. Batah, A. Fabro, T. Mauad, M. Dolhnikoff, A. Duarte-Neto, P. Saldiva, T. Cunha, J. Alves-Filho, E. Arruda, P. Louzada-Júnior, R. D. Oliveira, F. Cunha   +45 more
semanticscholar   +1 more source

Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases

Nature reviews. Immunology, 2022
Systemic autoimmune diseases are characterized by the failure of the immune system to differentiate self from non-self. These conditions are associated with significant morbidity and mortality, and they can affect many organs and systems, having ...
G. Wigerblad, M. Kaplan
semanticscholar   +1 more source

Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]

, 2012
Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
A Cederlund, A da Silva Dantas, Alistair J. P. Brown, B Amulic, B Enjalbert, B Enjalbert, B Hube, B Hube, BD Ullmann, Bernhard Hube, BH Youseff, BS Hromatka, C Fradin, Christine Dunker, CJ Barelle, CJ Barelle, CJ Heilmann, D Wilson, DA Smith, DL Moyes, DL Moyes, DM Arana, DR Wysong, FC Fang, GM Chaves, Hanna Windecker, I Rubin-Bejerano, I Wozniok, ID Jacobsen, IE Frohner, Iryna M. Bohovych, J Cheetham, M de Jesus-Berrios, M Martchenko, MA Wheeler, MC Lorenz, MC Lorenz, MG Netea, Oliver Kurzai, Oscar Zaragoza, P Nordenfelt, Pedro Miramón, R Alonso-Monge, R Pathania, RA Calderone, RI Lehrer, SC Cheng, TM Stevanin, TM Stevanin, V Brinkmann, W Bellamy, W Chiranand   +51 more
core   +6 more sources

Neutrophil activation and neutrophil derived neutrophil extracellular trap formation in patients with coronary artery ectasia

BMC Cardiovascular Disorders, 2020
Background This study investigated neutrophil activation and neutrophil-derived extracellular traps formation in coronary artery ectasia. Methods We enrolled 90 patients who underwent coronary angiography, and included 30 patients with coronary artery ...
Yuchao Guo, Ruifeng Liu, Lianfeng Chen, Wei Wu, Shuyang Zhang   +4 more
doaj   +1 more source