Results 41 to 50 of about 52,667 (297)

Neutrophil Extracellular Traps [PDF]

, 2019
Neutrophil extracellular traps (NETs) are made of a network of extracellular strings of DNA that bind pathogenic microbes. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms. Reactive oxygen species generated by the neutrophil NADPH oxidase have been shown to be essential to mediate NET ...
openaire   +2 more sources

Neutrophil Extracellular Traps (NETs) and Vasculitis [PDF]

International Journal of Medical Sciences, 2021
Background: Neutrophil extracellular traps (NETs) have been implicated in host immune responses. Attempts have been made to examine how NETs affect the pathogenesis of complications such as autoimmune and vascular disorders. Aim: This study aimed to explore the relationship between NETs and vasculitis.
Arneth, Borros, Arneth, Rebekka, Justus Liebig University Giessen   +2 more
openaire   +3 more sources

Neutrophil extracellular traps (NETs) : formation and implications [PDF]

, 2013
Neutrophils are cells of the immune system which freely circulate in blood vessels and are recruited to the inflammation sites when the human organism responds to microbial infections.
Rąpała-Kozik, Maria, Zawrotniak, Marcin   +1 more
core   +1 more source

Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]

, 2015
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall, AK Neumann, B Amulic, B Enjalbert, B Hube, BN Gantner, C Jiménez-López, C Sasse, C Tokarski, CC Sheth, CF Urban, CGJ McKenzie, CJ Chrisman, D Armstrong-James, D Ermert, D Liebl, D Vijayan, DA Silva da, DC Savage, DJ Krysan, E Moreno-Ruiz, EK Szabo, FM Rudkin, G Chamilos, G Vande Velde, GD Brown, GD Brown, H Ma, H Ma, I Rubin-Bejerano, IE Frohner, J Behnsen, J Chandra, J Maertens, J Perlroth, J Voigt, JM Bain, JM Tam, Judith Bain, K Konig, K Schäfer, K Seider, KM Brothers, L Romani, L Romani, Lars-Peter Erwig, LE Lewis, LE Lewis, LG Tilney, LY Ngo, M Alvarez, MC Lorenz, MG Netea, MJ Patterson, MS Lionakis, MS Lionakis, N Papon, NAR Gow, Neil A. R. Gow, O Uzun, O Zaragoza, P Martino, P Miramón, Q Qian, R García-Rodas, RA Drummond, RD Diamond, RI Lehrer, S Bruns, S El-Kirat-Chatel, S Keppler-Ross, S Mitra, SA Johnston, SC Cheng, SE Heinsbroek, V Aimanianda, Wellington, Y Luo   +77 more
core   +1 more source

Neutrophil Extracellular Traps Orchestrate Necroinflammation [PDF]

Journal of the American Society of Nephrology, 2017
In 1869, a young Swiss student who was interested in the study of the nuclei of cells succeeded in separating the nuclei from the cytoplasm of white blood cell from pus, which he obtained from discarded surgical bandages from the local surgical clinic.[1][1] He found that the nuclei were made of ...
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Neutrophil extracellular traps — the dark side of neutrophils [PDF]

Journal of Clinical Investigation, 2016
Neutrophil extracellular traps (NETs) were discovered as extracellular strands of decondensed DNA in complex with histones and granule proteins, which were expelled from dying neutrophils to ensnare and kill microbes. NETs are formed during infection in vivo by mechanisms different from those originally described in vitro. Citrullination of histones by
Sørensen, Ole E., Borregaard, Niels
openaire   +3 more sources

Neutrophil Extracellular Traps Formation and Aggregation Orchestrate Induction and Resolution of Sterile Crystal-Mediated Inflammation

Frontiers in Immunology, 2018
The formation of neutrophil extracellular traps (NETs) to immobilize pathogens represents a novel antimicrobial strategy of the immune system. The microcrystals related to human diseases are classified into endogenous microcrystals, including monosodium ...
Yanhong Li, Xue Cao, Yi Liu, Yi Zhao, Yi Zhao, Martin Herrmann   +5 more
doaj   +1 more source

Stroke-derived neutrophils demonstrate higher formation potential and impaired resolution of CD66b + driven neutrophil extracellular traps

BMC Neurology, 2022
Background Recent evidence suggests a merging role of immunothrombosis in the formation of arterial thrombosis. Our study aims to investigate its relevance in stroke patients. Methods We compared the peripheral immunological profile of stroke patients vs.
Angeliki Datsi, Laura Piotrowski, Markella Markou, Thomas Köster, Isabelle Kohtz, Kerstin Lang, Sabine Plöttner, Heiko Udo Käfferlein, Burkhard Pleger, Ramon Martinez, Bogdan Pintea, Roland Fried, Marcus Müller, Rene Chapot, Konstantinos Gousias   +14 more
doaj   +1 more source

Netosis in the pathogenesis of antiphospholipid syndrome and systemic lupus erythematosus

Современная ревматология, 2021
Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases. In recent years, APS has been considered as an autoimmune thrombo-inflammatory disease.
K. S. Nurbaeva, T. M. Reshetnyak, A. M. Lila   +2 more
doaj   +1 more source

Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]

, 2020
We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM, Hinds, J, Hossain, I, Hua, Y, Mackenzie, GA, Manna, S, Mulholland, EK, Ndiaye, M, Ortika, BD, Salaudeen, R, Satzke, C   +10 more
core   +4 more sources