Results 81 to 90 of about 75,140 (320)

Neutrophil Extracellular Traps and Cancer: Trapping Our Attention with Their Involvement in Ovarian Cancer

International Journal of Molecular Sciences, 2023
Neutrophils, the most abundant circulating leukocytes, play a well-known role in defense against pathogens through phagocytosis and degranulation. However, a new mechanism involving the release of neutrophil extracellular traps (NETs) composed of DNA ...
M. Castaño, S. Tomás-Pérez, E. González-Cantó, C. Aghababyan, Andrea Mascarós-Martínez, Nuria Santonja, A. Herreros-Pomares, J. Oto, P. Medina, M. Götte, B. M. Mc Cormack, J. Marí-Alexandre, J. Gilabert-Estellés   +12 more
semanticscholar   +1 more source

Ginsenoside Rb1 ameliorates neutrophil extracellular traps-induced vascular endothelial damage by suppressing apoptosis

Bangladesh Journal of Pharmacology
The study aims to investigate the effect of ginsenoside Rb1 on improving neutrophil extracellular traps-induced vascular endothelial damage. The CCK8 assay was used to evaluate the impact of ginsenoside Rb1 on cell activity.
Biao Zhang, Junkai Zhao, Jiamin Yin, Jiaping Chen, Lingqi Xu   +4 more
doaj   +1 more source

Janus-Faced Neutrophil Extracellular Traps in Periodontitis

Frontiers in Immunology, 2017
Periodontitis is characterized by PMN infiltration and formation of neutrophil extracellular traps (NETs). However, their functional role for periodontal health remains complex and partially understood.
Ljubomir Vitkov, Ljubomir Vitkov, Dominik Hartl, Bernd Minnich, Matthias Hannig   +4 more
doaj   +1 more source

Neutrophil extracellular traps in acute coronary syndrome

Journal of Inflammation, 2023
Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart failure, arrhythmia and even sudden death. It is the major cause of disability and death worldwide.
Yawen Wu, Shilin Wei, Xiangyang Wu, Yongnan Li, Xue Han   +4 more
doaj   +1 more source

Neutrophil Extracellular Traps in the Autoimmunity Context

Frontiers in Medicine, 2021
The formation of neutrophil extracellular traps (NETs) is a strategy utilized by neutrophils for capturing infective agents. Extracellular traps consist in a physical net made of DNA and intracellular proteins externalized from neutrophils, where ...
Maurizio Bruschi, Gabriella Moroni, Renato Alberto Sinico, Franco Franceschini, Micaela Fredi, Augusto Vaglio, Lorenzo Cavagna, Andrea Petretto, Federico Pratesi, Paola Migliorini, Angelo Manfredi, Giuseppe A. Ramirez, Pasquale Esposito, Simone Negrini, Barbara Trezzi, Giacomo Emmi, Domenico Santoro, Francesco Scolari, Stefano Volpi, Marta Mosca, Angela Tincani, Giovanni Candiano, Marco Prunotto, Enrico Verrina, Andrea Angeletti, Angelo Ravelli, Gian Marco Ghiggeri, Gian Marco Ghiggeri   +27 more
doaj   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease [PDF]

, 2017
BACKGROUND: Neutrophil extracellular traps (NETs) have been observed in the airway in COPD, but their clinical and pathophysiological implications have not been defined.OBJECTIVE: To determine if NETs are associated with disease severity in COPD, and how
Agusti, Alison J. Dicker, Andrew J. Cassidy, Bafadhel, Branzk, Brinkmann, Calverley, Caporaso, Caudrillier, Celli, Christopher J. Fong, Colin N.A. Palmer, Dickson, Donnelly, Dworski, Eleanor G. Pumphrey, Elizabeth Furrie, Farnworth, Flynn, Gill Brady, Gisli G. Einarsson, Grabcanovic-Musija, Gray, Greenwood, Guillermo Suarez-Cuartin, Haslett, Hoenderdos, J. Stuart Elborn, James D. Chalmers, Jiang, Juneau, Kessenbrock, Khandpur, Knight, Lange, Leidy, Lozano, Megan L. Crichton, Menegazzi, Metzler, Morris, Obermayer, Oriol Sibila, Papayannopoulos, Pascoe, Pavord, Pedersen, Richens, Sara E. Marshall, Savill, Sayah, Short, Speizer, Stuart Schembri, Vestbo, Wasyla Ibrahim, Willemse, Yipp, Zabieglo   +58 more
core   +2 more sources

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Journal of Cell Biology, 2010
Neutrophil elastase escapes azurophilic granules, translocates to the nucleus, and degrades histones to promote chromatin decondensation necessary for NET formation.
V. Papayannopoulos, Kathleen D. Metzler, Abdul Hakkim, A. Zychlinsky   +3 more
semanticscholar   +1 more source

Neutrophil extracellular traps promote metastasis in gastric cancer patients with postoperative abdominal infectious complications

Nature Communications, 2022
Postoperative abdominal infectious complication (AIC) is associated with metastasis in locally advanced gastric cancer (GC) patients after radical gastrectomy. However, the underlying mechanism remains unclear.
X. Xia, Zizhen Zhang, Chunchao Zhu, B-L Ni, Shuchang Wang, Shuofei Yang, Fengrong Yu, E. Zhao, Qing Li, Gang Zhao   +9 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source