Results 241 to 250 of about 845,167 (291)

Pathogenesis of hidradenitis suppurativa: From susceptibility to chronicity

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review describes hidradenitis suppurativa as a heterogeneous disorder in which genetic susceptibility, epithelial dysfunction, environmental exposures, immune activation and microbial ecology converge differently across patients and disease stages.
Kelsey R. van Straalen, Nisha S. Chandran, Jean M. Fletcher, Evangelos J. Giamarellos‐Bourboulis, Elia Rosi, Gregor B. E. Jemec   +5 more
wiley   +1 more source

Obesity‐associated transcriptomic remodelling in hidradenitis suppurativa and treatment response

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review highlights that adiposity systemically primes HS through adipokine dysregulation and insulin resistance, contributing to lesional metabolic reprogramming and perilesional barrier dysfunction. Current evidence indicates that obesity exacerbates disease severity and attenuates responses to biologic therapies, supporting the classification of ...
Sahil Kapur, Xzaviar K. Solone, Randy Mi, Kermanjot S. Sidhu, Meyer Gershater, Jeffrey Cruz, Iltefat Hamzavi, Indra Adrianto, Li Zhou, Qing‐Sheng Mi   +9 more
wiley   +1 more source

The Dual Role of Neutrophil Extracellular Traps (NETs) in Sepsis and Ischemia-Reperfusion Injury: Comparative Analysis across Murine Models. [PDF]

Int J Mol Sci
Kiwit A, Lu Y, Lenz M, Knopf J, Mohr C, Ledermann Y, Klinke-Petrowsky M, Pagerols Raluy L, Reinshagen K, Herrmann M, Boettcher M, Elrod J.   +11 more
europepmc   +1 more source

napari‐lattice: A user‐friendly image processing tool for lattice light‐sheet microscopy data

Journal of Microscopy, EarlyView.
Abstract Lattice light‐sheet microscopy (LLSM) has revolutionised live‐cell imaging with its ability to resolve sub‐cellular detail with high spatiotemporal resolution and minimal phototoxicity. However, LLSM often generates large terabyte‐scale datasets that require complex preprocessing, creating bottlenecks in storage, data handling and analysis ...
Pradeep Rajasekhar, Michael Milton, Niall D. Geoghegan, Ishrat Zaman, George W. Ashdown, Robert Haase, Julie Iskander, Anna K. Coussens, Kelly L. Rogers, Lachlan Whitehead   +9 more
wiley   +1 more source

Use of Platelet‐Rich Fibrin (PRF) on Palatal Wound Healing: A Narrative Review With Clinical Recommendations

Journal of Periodontal Research, EarlyView.
Based on the available evidence, the application of platelet‐rich fibrin (PRF) following free gingival graft (FGG) and subepithelial connective tissue graft (SCTG) harvesting appears to be a promising approach for enhancing wound healing, minimizing postoperative complications, and reducing analgesic consumption. ABSTRACT This clinical narrative review
Nima Farshidfar, Paras Ahmad, Nathan Estrin, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source

Neutrophil Extracellular Traps (NETs) Are Associated with Type 2 Diabetes and Diabetic Foot Ulcer Related Amputation: A Prospective Cohort Study. [PDF]

Diabetes Ther
Ibrahim I, Nuermaimaiti Y, Maimaituxun G, Luo X, Maimaituxun M, Akbar A, Tuerxun K, Wu Y.   +7 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer. [PDF]

Cell Death Dis
Zhang F, Yan Y, Cao X, Guo C, Wang K, Lv S.   +5 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

The Bifunctional Effects of Lactoferrin (LFcinB11) in Inhibiting Neural Cell Adhesive Molecule (NCAM) Polysialylation and the Release of Neutrophil Extracellular Traps (NETs). [PDF]

Int J Mol Sci
Lu B, Liao SM, Liang SJ, Peng LX, Li JX, Liu XH, Huang RB, Zhou GP.   +7 more
europepmc   +1 more source