Results 31 to 40 of about 22,874 (254)
Simplified Human Neutrophil Extracellular Traps (NETs) Isolation and Handling [PDF]
Journal of Visualized Experiments, 2015 Neutrophil Extracellular Traps (NETs) have been recently identified as part of the neutrophil's antimicrobial armamentarium. Apart from their role in fighting infections, recent research has demonstrated that they may be involved in many other disease processes, including cancer progression.
Sara, Najmeh +4 more
openaire +2 more sources
Netting Gut Disease: Neutrophil Extracellular Trap in Intestinal Pathology
Oxidative Medicine and Cellular Longevity, 2021 Many gut disease etiologies are attributed to the presence of robust inflammatory cell recruitment. The recruitment of neutrophils plays a vital role in inflammatory infiltration. Neutrophils have various antimicrobial effector mechanisms, including phagocytosis, oxidative burst, and degranulation.
Kai Chen +12 more
openaire +2 more sources
Neutrophil extracellular traps and complications of liver transplantation
Frontiers in Immunology, 2022 Many end-stage liver disease etiologies are attributed to robust inflammatory cell recruitment. Neutrophils play an important role in inflammatory infiltration and neutrophil phagocytosis, oxidative burst, and degranulation.
Yanyao Liu +5 more
doaj +1 more source
M1 Macrophages Drive Cxcr2+ Netosis Via Cxcl8/Cxcr2 In Pulpitis
International Dental JournalAim or purpose: To elucidate how M1 macrophages exacerbate pulpitis by driving CXCR2+ neutrophil extracellular traps (NETs) formation via the CXCL8/CXCR2 signaling axis. Materials and methods: We performed single-cell RNA sequencing (scRNA-seq) on normal
Ruilin Zhang
doaj +1 more source
mBio, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is leading to public health crises worldwide. An understanding of the pathogenesis and the development of treatment strategies is of high interest.
Nicole de Buhr +1 more
doaj +1 more source
, 2019 As we have learned during recent years, neutrophils are not just simple foot soldiers of the innate immune system with a restricted set of pro-inflammatory functions, and instead, they perform sophisticated functions (some of them only recently discovered) both in innate and adaptive immune responses.
Cichoń, Iwona +3 more
openaire +3 more sources
ETosis: A Microbicidal Mechanism beyond Cell Death
Journal of Parasitology Research, 2012 Netosis is a recently described type of neutrophil death occurring with the release to the extracellular milieu of a lattice composed of DNA associated with histones and granular and cytoplasmic proteins.
Anderson B. Guimarães-Costa +4 more
doaj +1 more source
In vitro Demonstration and Quantification of Neutrophil Extracellular Trap Formation
Bio-Protocol, 2017 In the recent decade, neutrophil extracellular traps (NETs) have been identified and confirmed as a new anti-microbial weapon of neutrophils. In this protocol, we describe easy methods to demonstrate NET formation by immunofluorescence staining of ...
Dongsheng Jiang +2 more
doaj +1 more source
Resistance of hypervirulent Klebsiella pneumoniae to both intracellular and extracellular killing of neutrophils. [PDF]
PLoS ONE, 2017 Hypervirulent Klebsiella pneumoniae (HvKP) is hypermucoviscous organism, carrying genes of rmpA and aerobactin, causing serious community-acquired infection and metastatically spread in young healthy hosts.
Lifeng Wang +3 more
doaj +1 more source
Neutrophil Extracellular Traps in Digestive Cancers: Warrior or Accomplice
Frontiers in Oncology, 2021 Characterized as a complex of extracellular DNA fibers and granule proteins, neutrophil extracellular traps (NETs) are generated specifically by neutrophils which play a critical role in host defense and immune regulation.
Yuxin Chen +11 more
doaj +1 more source