Results 81 to 90 of about 845,167 (291)

Neutrophils Cast Extracellular Traps in Response to Protozoan Parasites

Frontiers in Immunology, 2012
Release of extracellular traps by neutrophils is a now well-established phenomenon that contributes to the innate response to extracellular bacterial and fungal pathogens.
Eric eDenkers, Delbert eAbi Abdallah
doaj   +1 more source

Physical exercise, obesity, inflammation and neutrophil extracellular traps (NETs): a review with bioinformatics analysis

, 2021
Neutrophil extracellular traps (NETs) represent an innate organism defense mechanism characterized by neutrophil release of intracellular material to capture any aggressor agent.
Jaciara Neves Sousa, Sérgio Henrique Sousa Santos, Daniela Fernanda de Freitas, Renato Sobral Monteiro Júnior, Victor Hugo Dantas Guimarães, Iara Heloisa Ramos Mendes, Berenilde Valéria de Oliveira Sousa   +6 more
core   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Clinical significance of determining neutrophil extracellular traps in women with oncogynecological neoplasms

Акушерство, гинекология и репродукция
The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community.
Z. D. Aslanova, J. Kh. Khizroeva, A. G. Solopova, V. A. Solodkiy, A. V. Vorobev, D. V. Blinov, M. D. Aslanova, I. A. Nakaidze, J.-C. Gris, I. Elalamy, A. D. Makatsariya   +10 more
doaj   +1 more source

Neutrophil extracellular traps in cattle health and disease

, 2021
Neutrophils largely contribute to the first line of defense against the invasion of pathogens. They kill pathogens basically by the following mechanisms: phagocytosis and proteolytic degradation, the release of enzymes with bactericidal activities, and ...
Xie, Lei, Opsomer, Geert, Ma, Yixiong, Bogado Pascottini, Osvaldo Américo, Dong, Qiang, Guan, Yandong, Pascottini, Osvaldo Bogado, Lei Xie, Yixiong Ma, Geert Opsomer, Osvaldo Bogado Pascottini, Qiang Dong, Yandong Guan   +12 more
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Neutrophil Extracellular Traps: The Biology of Chromatin Externalization [PDF]

, 2018
Neutrophils are essential to the homeostatic mission of safeguarding host tissues, responding rapidly and diversely to breaches of the host's barriers to infection, and returning tissues to a sterile state.
Tilley, Dorothea Ogmore, Gabriel Sollberger, Sollberger, G., Zychlinsky, A., Tilley, D., Sollberger, Gabriel, Arturo Zychlinsky, Zychlinsky, Arturo, Dorothea Ogmore Tilley   +8 more
core   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

Advanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun, Hengjie Xu, Sheng Yang, Jiahui Zhou, Chuanxin Tian, Hongxu Nie, Chi Jin, Tuo Wang, Zhihao Chen, Junwei Tang, Yifei Feng, Xiaowei Wang, Yueming Sun   +12 more
wiley   +1 more source

Clinical Implications of Excessive Neutrophil Extracellular Trap Formation in Renal Autoimmune Diseases

Kidney International Reports, 2019
Neutrophil extracellular traps (NETs) are extracellular DNA structures covered with antimicrobial peptides, danger molecules, and autoantigens that can be released by neutrophils.
Laura S. van Dam, Ton J. Rabelink, Cees van Kooten, Y.K. Onno Teng   +3 more
doaj   +1 more source