Results 61 to 70 of about 845,167 (291)

Neutrophil extracellular traps in acute coronary syndrome

, 2023
Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart failure, arrhythmia and even sudden death. It is the major cause of disability and death worldwide.
Yawen Wu, Yongnan Li, Xue Han, Shilin Wei, Xiangyang Wu   +4 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Knotting the NETs: Analyzing histone modifications in neutrophil extracellular traps [PDF]

Arthritis Research & Therapy, 2012
Neutrophil extracellular chromatin traps (NETs) are a recently described mechanism of innate immune responses to bacteria and fungi. Evidence indicates that NETs are induced by inflammation, that they contribute to diverse disease pathologies, and that they associate with bactericidal substances. Genomic DNA is released in NETs, leading to a cell death
Neeli, Indira, Radic, Marko
openaire   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Consideration of dornase alfa for the treatment of severe COVID-19 acute respiratory distress syndrome

New Microbes and New Infections, 2020
We propose a likely contribution to severe COVID-19 morbidity by extracellular DNA in neutrophil extracellular traps (NETs). Dornase alfa degrades extracellular DNA to reduce mucus rigidity and accumulation, and was associated with respiratory ...
A.P. Earhart, Z.M. Holliday, H.V. Hofmann, A.G. Schrum   +3 more
doaj   +1 more source

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

, 2009
Neutrophil extracellular traps (NETs) represent extracellular structures able to bind and kill microorganisms. It is believed that they are generated by neutrophils undergoing cell death, allowing these dying or dead cells to kill microbes. We show that,
E Kozlowski, Kozlowski, E, I Schmid, Simon, H U, Schmid, I, S Yousefi, H U Simon, Yousefi, S, Mihalache, C, C Mihalache, Yousefi S, Kozlowski E, Yousefi, Shida, Simon HU, Mihalache C, Schmid I, Simon, Hans-Uwe   +16 more
core   +1 more source

Neutrophil extracellular traps in colorectal cancer progression and metastasis

, 2021
Neutrophils form sticky web-like structures known as neutrophil extracellular traps (NETs) as part of innate immune response. NETs are decondensed extracellular chromatin filaments comprising nuclear and cytoplasmic proteins. NETs have been implicated in
Md Morsaline Billah, Thorlacius, Henrik, Billah, Md Morsaline, Rahman, Milladur, Sabrina Chowdhury, Milladur Rahman, Umama Khan, Chowdhury, Sabrina, Islam, Kazi Mohammed Didarul, Khan, Umama, Kazi Mohammed Didarul Islam, Henrik Thorlacius, Rahman, Milladur,, Khan, Umama,, Islam, Kazi Mohammed Didarul,, Billah, Md Morsaline,, Thorlacius, Henrik,, Chowdhury, Sabrina,, Lund University.   +18 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

On the Origin of Neutrophil Extracellular Traps in COVID-19

Frontiers in Immunology, 2022
Despite ongoing vaccination COVID-19 is a global healthcare problem because of the lack of an effective targeted therapy. In severe COVID-19 manifesting as acute respiratory distress syndrome, uncontrolled innate immune system activation results in ...
Michal Pastorek, Martin Dúbrava, Peter Celec, Peter Celec, Peter Celec   +4 more
doaj   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source