Results 51 to 60 of about 14,053 (187)

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

NGAL (Neutrophil Gelatinase-Associated Lipocalin) as an early biomarker of nephropathy in patients with type 2 diabetes

open access: yesAlexandria Journal of Medicine, 2023
Background and aim Diabetic nephropathy (DN) is a major microvascular diabetic complication representing the key leading reason for end-stage renal disease (ESRD).
Magdy Helmy Zikry Megallaa   +4 more
doaj   +1 more source

Neutrophil gelatinase-associated lipocalin as a biomarker for the diagnosis of urinary tract infection in children

open access: yesMedicine Science, 2022
Urinary tract infection (UTI) is common in childhood and may have important consequences. The reference standard for the diagnosis is urine culture, but it requires time for bacterial growth.
Utku Pamuk   +3 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

The Landscape of Biomarkers in ICU‐Associated AKI: From Protein Markers to Cell‐Free Nucleic Acids

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Acute kidney injury (AKI) in critically ill patients—particularly in sepsis—often develops early and is missed by creatinine/urine output–based criteria, delaying risk stratification and timely intervention. This review synthesizes current evidence on established and emerging AKI biomarkers (e.g., NGAL, KIM‐1, [TIMP‐2]·[IGFBP7]) alongside circulating ...
Qi Zhu   +10 more
wiley   +1 more source

Serum neutrophil gelatinase-associated lipocalin in obese adolescents

open access: yesBulletin of the National Research Centre, 2018
Background Nonalcoholic fatty liver disease (NAFLD) is an emerging clinical problem among obese adolescents. Methods This study was conducted on 40 obese adolescents, previously diagnosed by ultrasonography to determine liver status and confirmed to have
Wafaa A. Kandeel   +8 more
doaj   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

Comparative Study between Neutrophil Gelatinase-Associated Lipocalin [NGAL] versus C - Reactive Protein for Detection of Acute Kidney Injury in Sepsis at Intensive Care Unit [PDF]

open access: yesInternational Journal of Medical Arts
Background: Neutrophil gelatinase-associated lipocalin [NGAL], a protein associated with neutrophil gelatinase, shows potential as a new biomarker that can indicate the severity and outcome of acute kidney injury [AKI].
Abdelrahman Mansour   +3 more
doaj   +1 more source

Diagnostic accuracy of neutrophil gelatinase-associated lipocalin as a predictor of chronic kidney disease

open access: yesJournal of Medicine in Scientific Research, 2021
Introduction Chronic kidney disease (CKD) is a major threat to public health problem, in terms of prevalence of disease, cost of treatment, and the comorbidities involved. To screen out the severe disease earlier and more accurately, estimated glomerular
Azza Ali I. Elmenyawi, Ahmed H Elthakaby
doaj   +1 more source

Association of peripheral blood neutrophil gelatinase‐associated lipocalin levels with bone marrow neutrophil gelatinase‐associated lipocalin levels and neutrophil count in hematologic malignancy [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2019
AbstractBackgroundAlthough neutrophil gelatinase‐associated lipocalin (NGAL) is a biomarker for acute kidney injury, recently, high NGAL levels have been reported in hematologic malignancies. Given the mechanism underlying NGAL synthesis and secretion in neutrophilic series, it is speculated that NGAL levels are higher in bone marrow (BM) than in ...
Chi‐Hyun Cho   +5 more
openaire   +2 more sources

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