Results 141 to 150 of about 1,037,717 (382)

Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease

Cell and Tissue Research, 2018
Neutrophils are becoming recognized as highly versatile and sophisticated cells that display de novo synthetic capacity and potentially prolonged lifespan.
Kathryn Prame Kumar, Alyce J. Nicholls, Connie H. Y. Wong   +2 more
semanticscholar   +1 more source

Group V Phospholipase A2 Induces Leukotriene Biosynthesis in Human Neutrophils through the Activation of Group IVA Phospholipase A2 [PDF]

, 2002
We reported previously that exogenously added human group V phospholipase A2 (hVPLA2) could elicit leukotriene B4 (LTB4) biosynthesis in human neutrophils (Han, S. K., Kim, K. P., Koduri, R., Bittova, L., Munoz, N. M., Leff, A. R., Wilton, D. C., Gelb, M.
Cho, Wonhwa, Han, Sang Kyou, Kim, Kwang Pyo, Kim, Young Jun, Leff, Alan R., Munoz, Nilda M., Sano, Hiroyuki, Zhu, Xiangdong   +7 more
core   +1 more source

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Journal of Experimental Medicine, 2012
Deep vein thrombosis initiation is mediated by cross talk between monocytes, neutrophils, and platelets.
Marie-Luise von Brühl, K. Stark, Alexander Steinhart, S. Chandraratne, Ildiko Konrad, M. Lorenz, A. Khandoga, A. Tirniceriu, R. Coletti, Maria Koellnberger, Robert A. Byrne, I. Laitinen, A. Walch, A. Brill, S. Pfeiler, D. Manukyan, S. Braun, Philipp Lange, Julia Riegger, J. Ware, Annekathrin Eckart, Selgai Haidari, M. Rudelius, C. Schulz, Katrin Echtler, V. Brinkmann, M. Schwaiger, K. Preissner, D. Wagner, N. Mackman, B. Engelmann, S. Massberg   +31 more
semanticscholar   +1 more source

Loss of testosterone impairs anti-tumor neutrophil function. [PDF]

, 2020
In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent ...
Arditi, Moshe, Crother, Timothy R, Lane, Malcolm E, Luu, Michael, Markman, Janet L, Martinon, Daisy, Noval Rivas, Magali, Porritt, Rebecca A, Posadas, Edwin M, Wakita, Daiko   +9 more
core   +1 more source

The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice is a Major Cause of CNS Pathology Resulting in Fatal Encephalitis [PDF]

, 2008
This study was undertaken to investigate possible immune mechanisms in fatal HSV-1 encephalitis (HSE) after HSV-1 corneal inoculation. Susceptible 129S6 (129) but not resistant C57BL/6 (B6) mice developed intense focal inflammatory brainstem lesions of ...
Brown, Jeffrey, Cantin, Edouard M., Hamamura, Mark, Hinton, David R., Kovats, Susan, Lundberg, Patric, Nalcioglu, Orhan, Openshaw, Harry, Ramakrishna, Chandran, Tyszka, J. Michael, Weinberg, Kenneth   +10 more
core   +2 more sources

Quantitative Shape Irregularity and Density Heterogeneity Predict Hematoma Expansion in Patients With Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji, Yunyi Hao, Bin Gao, Xiaojing Zhang, Yani Zhang, Jiaokun Jia, Xue Xia, Yuhao Guo, Sijia Li, Jianwei Wu, Kaijiang Kang, Xingquan Zhao   +11 more
wiley   +1 more source

Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma

Cell Death and Disease, 2018
Emerging evidence indicate that cancer-associated fibroblasts (CAFs) affect tumor progression by reshaping the tumor microenvironment. Neutrophils are prominent components of solid tumors and important in cancer progression.
Yusheng Cheng, Hui Li, Yinan Deng, Y. Tai, K. Zeng, Yingcai Zhang, Wei Liu, Qi Zhang, Yang Yang   +8 more
semanticscholar   +1 more source

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo [PDF]

, 2013
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the
Afonso, P., Angermann, B., Germain, R., Kastenmüller, W., Lämmermann, T., Parent, C., Wang, J.   +6 more
core   +2 more sources

The neutrophile count [PDF]

Tubercle, 1920
n ...
openaire   +3 more sources

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source