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Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses.
Nico Reusch +16 more
doaj +2 more sources
The regulatory roles of neutrophils in adaptive immunity
Neutrophils have long been considered as cells playing a crucial role in the immune defence against invading pathogens. Accumulating evidence strongly supported the direct and indirect regulatory effects of neutrophils on adaptive immunity.
Yang Li +5 more
doaj +2 more sources
Neutrophils are the most abundant white blood cells and are the first recruited to inflammatory sites. Neutrophils are an important component of the tumor stroma and can exert both anti-tumoral and pro-tumoral activities, depending on their maturation ...
Matteo Massara +12 more
doaj +4 more sources
Neutrophils in chronic inflammatory diseases
Chronic inflammation is a component of many disease conditions that affect a large group of individuals worldwide. Chronic inflammation is characterized by persistent, low-grade inflammation and is increased in the aging population.
Andrea Herrero-Cervera +2 more
semanticscholar +1 more source
Multiple Death Pathways of Neutrophils Regulate Alveolar Macrophage Proliferation
Alveolar macrophage (AM) proliferation and self-renewal play an important role in the lung tissue microenvironment. However, the impact of immune cells, especially the neutrophils, on AM homeostasis or function is not well characterized.
Xiaochen Gao +8 more
doaj +1 more source
Increased Circulating of CD54highCD181low Neutrophils in Myelodysplastic Syndrome
Myelodysplastic syndromes (MDSs) are a group of heterogeneous hematopoietic stem/progenitor cells clonal diseases, characteristic features with myeloid dysplasia, leading to abnormality of neutrophils.
Liyan Yang +8 more
doaj +1 more source
Neutrophils in cancer carcinogenesis and metastasis
In recent years, neutrophils have attracted increasing attention because of their cancer-promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic indicator for patients with cancer.
Shumin Xiong, Liaoliao Dong, Lin Cheng
semanticscholar +1 more source
Neutrophils constitute abundant cellular components in atherosclerotic plaques. Most of the current studies are focused on the roles of granular proteins released by neutrophils in atherosclerosis.
Tingrui Zhao +31 more
doaj +1 more source
Background Neutrophils are the most prevalent immune cells in the synovial fluid in inflamed joints of children with oligoarticular juvenile idiopathic arthritis (JIA).
Sabine Arve-Butler +7 more
doaj +1 more source
Tumor-associated neutrophils and neutrophil-targeted cancer therapies.
Neutrophils are the frontline cells in response to microbial infections and are involved in a range of inflammatory disorders in the body. In recent years, neutrophils have gained considerable attention in their involvement of complex roles in tumor ...
Haiying Que +4 more
semanticscholar +1 more source

