Results 21 to 30 of about 486,846 (263)
Frontiers in Immunology, 2022 Neutrophils are highly abundant in synovial fluid of rheumatic inflamed joints. In oligoarticular juvenile idiopathic arthritis (JIA), synovial fluid neutrophils have impaired effector functions and altered phenotype.
Sabine Arve-Butler +12 more
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Immunological Reviews, 2016 Summary Neutrophils play an important role in cancer. This does not only relate to the well‐established prognostic value of the presence of neutrophils, either in the blood or in tumor tissue, in the context of cancer progression or for the monitoring of therapy, but also to their active role in the progression of
Treffers, Louise W +4 more
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Neutrophils: New Critical Regulators of Glioma
Frontiers in Immunology, 2022 In cancer, neutrophils are an important part of the tumour microenvironment (TME). Previous studies have shown that circulating and infiltrating neutrophils are associated with malignant progression and immunosuppression in gliomas.
Guanyu Wang +11 more
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Understanding the Multifaceted Role of Neutrophils in Cancer and Autoimmune Diseases
Frontiers in Immunology, 2018 Neutrophils are one of the first immune cell types that are recruited to injury and infection site. As a vital component of the immune system, neutrophils are heterogeneous immune cells known to have phagocytic property and function in inflammation ...
Xu Wang +14 more
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Cell Cycle, 2015 Neutrophils are short-lived effector cells of the innate immune system that form the first line of defense against microbial pathogens.1 Recent studies show that, by migrating to bone marrow, these cells can also induce (VACV)-specific T cell responses.2 Neutrophils polarize to distinct phenotypes in response to environmental cytokine/chemokine signals.
Mauro, Di Pilato, Mariano, Esteban
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Frontiers in Immunology, 2021 Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses.
Nico Reusch +16 more
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Clinical & Translational Immunology, 2022 Objectives Immune thrombocytopenia (ITP) is an autoimmune disease characterised by impaired platelet production and increased platelet destruction. However, the involvement of neutrophils in ITP is yet to be explored.
Pengcheng Xu +12 more
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Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine
Cellular Physiology and Biochemistry, 2017 Background/Aims: Cystic fibrosis (CF) is dominated by chronic inflammation and infection of the lung resulting in lung destruction and early death of patients. The lungs of CF patients are characterized by a massive accumulation of neutrophils.
Katrin Anne Becker +9 more
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ERJ Open Research, 2015 In the airways of severe asthmatics, an increase of neutrophils and eosinophils is often observed despite high-dose corticosteroid therapy. We previously reported that interleukin-8-stimulated neutrophils induced trans-basement membrane migration (TBM ...
Fuyumi Nishihara +7 more
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Frontiers in Medicine, 2022 Transfusion of granulocyte concentrates (GC) is an alternative therapy for neutropenic patients with life-threatening infections. While neutrophils are the main source of antimicrobial activity, only neutrophil numbers are used to certify GCs.
Andréa Murru +19 more
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