Dexamethasone and RU24858 induce survival and growth factor receptor bound protein 2, leukotriene B4 receptor 1 and annexin-1 expression in primary human neutrophils [PDF]
, 2012 Glucocorticoids are widely used anti-inflammatory medication in diseases like asthma and chronic obstructive pulmonary disease. Glucocorticoids can either activate (transactivation) or inhibit (transrepression) transcription. RU24858 was introduced as a
Adcock, I +4 more
core +3 more sources
An Attempt to Polarize Human Neutrophils Toward N1 and N2 Phenotypes in vitro
Frontiers in Immunology, 2020 Neutrophils act as the first line of defense against invading pathogens. Although traditionally considered in context of their antimicrobial effector functions, the importance of tumor-associated neutrophils (TANs) in the development of cancer has become
Mareike Ohms, Sonja Möller, T. Laskay
semanticscholar +1 more source
Cell type-specific differences in β-glucan recognition and signalling in porcine innate immune cells [PDF]
, 2014 β-glucans exert receptor-mediated immunomodulating activities, including oxidative burst activity and cytokine secretion. The role of the β-glucan receptors dectin-1 and complement receptor 3 (CR3) in the response of immune cells towards β-glucans is ...
Adachi +55 more
core +2 more sources
AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma. [PDF]
, 2012 AHNAK/Desmoyokin is a giant protein which has been recently linked to reorganization of the actin cytoskeleton, cellular migration and invasion. Here, we investigated the role of AHNAK in the pathophysiology of larynx carcinoma-one of the major subtypes ...
Bankfalvi, Agnes +5 more
core +5 more sources
Mineral trioxide aggregate induces the release of matrix metalloproteinase-9 by human neutrophils
Journal of Dental Sciences, 2013 Background/purpose: As a pulp capping agent, mineral trioxide aggregate (MTA) is commonly applied on inflamed tissues that present with a variety of immunocompetent cells, including neutrophils. Neutrophils are a major source of matrix metalloproteinases
Ya-Yun Lee +5 more
doaj +1 more source
Fatty acid transporter 2 reprograms neutrophils in cancer
Nature, 2019 Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) are pathologically activated neutrophils that are crucial for the regulation of immune responses in cancer.
F. Veglia +24 more
semanticscholar +1 more source
Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19
Cells, 2020 The COVID-19 pandemic is progressing worldwide with an alarming death toll. There is an urgent need for novel therapeutic strategies to combat potentially fatal complications.
Bhawna Tomar +3 more
semanticscholar +1 more source
In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury [PDF]
, 2006 Background: Intravenous salbutamol (albuterol) reduces lung water in patients with the acute respiratory distress syndrome (ARDS). Experimental data show that it also reduces pulmonary neutrophil accumulation or activation and inflammation in ARDS ...
McAuley, Daniel F. +4 more
core +2 more sources
Laboratory Animal Research, 2021 Increases of neutrophils and osteoclasts are pathological changes of periodontitis. RANKL is an osteoclast differentiation factor. The effect of periodontopathogen LPS on RANKL-expressing neutrophils has not been clarified yet.
Ae Ri Kim +4 more
doaj +1 more source
Neutrophils in respiratory viral infections
Mucosal Immunology, 2021 Viral respiratory infections are a common cause of severe disease, especially in infants, people who are immunocompromised, and in the elderly. Neutrophils, an important innate immune cell, infiltrate the lungs rapidly after an inflammatory insult.
C. Johansson, F. Kirsebom
semanticscholar +1 more source