Results 71 to 80 of about 23,399,129 (120)

Glycoprotein-Specific Polyclonal Antibodies Targeting Machupo Virus Protect Guinea Pigs against Lethal Infection

Vaccines
Convalescent plasma has been shown to be effective at protecting humans against severe diseases caused by New World (NW) arenaviruses, including Junin virus (JUNV) and Machupo virus (MACV).
Joseph W. Golden, Steven A. Kwilas, Jay W. Hooper   +2 more
doaj   +1 more source

The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor. [PDF]

PLoS Neglected Tropical Diseases, 2016
Machupo virus (MACV), a New World arenavirus, is the etiological agent of Bolivian hemorrhagic fever (BHF). Junin virus (JUNV), a close relative, causes Argentine hemorrhagic fever (AHF).
Takaaki Koma, Cheng Huang, Judith F Aronson, Aida G Walker, Milagros Miller, Jeanon N Smith, Michael Patterson, Slobodan Paessler   +7 more
doaj   +1 more source

Preparedness of Emergency Room Nurses for Bioterrorism Based on the Health Belief Model: A Multicenter Qualitative Study

International Nursing Review, Volume 72, Issue 2, June 2025.
ABSTRACT Aim To explore emergency room nurses’ perceptions of preparedness for bioterrorism. Introduction In the context of evolving global security threats, including wars, terrorism, and emerging infectious diseases, it is critical to evaluate the bioterrorism response competencies of emergency room nurses and identify strategies to enhance their ...
Mi‐Kyeong Jeon, Yujeong Kim
wiley   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

The structure of the Lujo virus spike complex

Nature Communications
Lujo virus (LUJV) is a human pathogen that was the cause of a deadly hemorrhagic fever outbreak in Africa. LUJV is a divergent member of the Arenaviridae with some similarities to both the “Old World” and “New World” serogroups, but it uses a cell-entry ...
Maayan Eilon-Ashkenazy, Hadas Cohen-Dvashi, Sarah Borni, Ron Shaked, Rivka Calinsky, Yaakov Levy, Ron Diskin   +6 more
doaj   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Identification of the dietary supplement capsaicin as an inhibitor of Lassa virus entry

Acta Pharmaceutica Sinica B, 2020
The limited treatment options for the increasing occurrence of Lassa hemorrhagic fever in West Africa poses an urgent need for the discovery and development of novel therapeutics.
Ke Tang, Xiaoyu Zhang, Ying Guo
doaj   +1 more source

Fiebres hemorrágicas por Arenavirus en Latinoamérica [PDF]

, 2010
ResumenLas fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicosen África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribuciónmundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que ...
Ella Patricia Soto Gomez, Salim Mattar Velilla   +1 more
core   +3 more sources

The Lassa Virus Stable Signal Peptide Undergoes a Conformational Change to Aid Viral Fusion

Chemistry – A European Journal, Volume 31, Issue 18, March 25, 2025.
The unique stable signal peptide (SSP) of the Lassa virus glycoprotein complex undergoes a conformational change during pH‐dependent viral fusion. This revels a potential mechanism by which the enigmatic SSP influences the fusion process through interactions it makes with the fusion protein, glycoprotein 2 (GP2).
Shane D. Collins, Liqun Jiang, Yanxin Liu, Jinwoo Lee   +3 more
wiley   +1 more source

From World Development Indicators

, 2017
The Atlas of Sustainable Development Goals 2017 uses maps, charts and analysis to illustrate, trends, challenges and measurement issues related to each of the 17 Sustainable Development Goals.
World Bank
core   +1 more source