Results 81 to 90 of about 23,399,129 (120)

Entry inhibitors as arenavirus antivirals

Frontiers in Microbiology
Arenaviruses belonging to the Arenaviridae family, genus mammarenavirus, are enveloped, single-stranded RNA viruses primarily found in rodent species, that cause severe hemorrhagic fever in humans. With high mortality rates and limited treatment options,
Kruthika Iyer, Zhonghao Yan, Susan R. Ross   +2 more
doaj   +1 more source

Identification, Characterization, and In Vitro Culture of Highly Divergent Arenaviruses from Boa Constrictors and Annulated Tree Boas: Candidate Etiological Agents for Snake Inclusion Body Disease

mBio, 2012
Inclusion body disease (IBD) is an infectious fatal disease of snakes typified by behavioral abnormalities, wasting, and secondary infections. At a histopathological level, the disease is identified by the presence of large eosinophilic cytoplasmic ...
Mark D. Stenglein, Chris Sanders, Amy L. Kistler, J. Graham Ruby, Jessica Y. Franco, Drury R. Reavill, Freeland Dunker, Joseph L. DeRisi   +7 more
doaj   +1 more source

Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses.

PLoS Pathogens, 2009
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever.
Jonathan Abraham, Jo Ann Kwong, César G Albariño, Jiajie G Lu, Sheli R Radoshitzky, Jorge Salazar-Bravo, Michael Farzan, Christina F Spiropoulou, Hyeryun Choe   +8 more
doaj   +1 more source

A hTfR1 Receptor-Specific VHH Antibody Neutralizes Pseudoviruses Expressing Glycoproteins from Junín and Machupo Viruses

Viruses
The Junín virus (JUNV) is one of the New World arenaviruses that cause severe hemorrhagic fever. Human transferrin receptor 1 (hTfR1) has been identified as the main receptor for JUNV for virus entry into host cells.
Qinglin Kang, Gege Li, Yan Wu, Shaoyan Wang, Zhengshan Chen, Xiaodong Zai, Xiaoyan Pan, Rong Wang, Jiansheng Lu, Peng Du, Zhixin Yang, Xiangyang Chi, Gengfu Xiao, Junjie Xu   +13 more
doaj   +1 more source

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

mSphere, 2018
Arenaviruses pose a major public health threat and cause numerous infections in humans each year. Although most viruses belonging to this family do not cause disease in humans, some arenaviruses, such as Lassa virus and Machupo virus, are the etiological
Fatima Amanat, James Duehr, Lisa Oestereich, Kathryn M. Hastie, Erica Ollmann Saphire, Florian Krammer   +5 more
doaj   +1 more source

Public health implications of a new world arenavirus outbreak that occurred in Bolivia, 2019

Travel Medicine and Infectious Disease, 2021
João Toledo, Alison Paredes Torrez, Alvaro Terrazas, Jhemis T. Molina Gutiérrez, Armando Medina Ramírez, Carla Romero, Dina Condori, Gricel Alarcon de la Vega, Krista C. Swanson, Mark G. Kortepeter, Sylvain Aldighieri   +10 more
openaire   +2 more sources

Novel Arenavirus, Zambia

, 2011
To investigate arenavirus in Zambia, we characterized virus from the kidneys of 5 arenavirus RNA–positive rodents (Mastomys natalensis) among 263 captured.
Ladslav Moonga, Akihiro Ishii, Aaron S. Mweene, Yuka Thomas, Aiko Ohnuma, Bernard M. Hang’ombe, Ichiro Nakamura, Hirofumi Sawa, Ayato Takada   +8 more
core   +1 more source

Infecciones por arenavirus [PDF]

, 2017
Los síndromes infecciosos asociados a arenavirus en América del sur son cuatro: síndrome febril de origen viral; fiebres hemorrágicas con o sin compromiso neurológico; meningitis asépticas y meningo-encefalitis. Entre los Arenavirus del nuevo mundo, está
Salim Mattar V, Calderón R, Alfonso, Mattar V, Salim, Camilo Guzmán T, Alfonso Calderón R, Guzmán T, Camilo, González Tous, Marco, Marco González Tous   +7 more
core   +1 more source

World Development Indicators 2009

, 2009
World Development Indicators (WDI) 2009 arrives at a moment of great uncertainty for the global economy. The crisis that began more than a year ago in the U.S. housing market spread to the global financial system
World Bank
core   +1 more source

Environment Matters at the World Bank : Annual Review 2005 [PDF]

, 2005
In line with one of the major themes in the Bank's Environment Strategy, this 2005 annual review is devoted to the theme of environmental health. Viewpoint articles in this edition reflect several external
World Bank
core   +1 more source