Results 61 to 70 of about 849,858 (379)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Cadmium in newborns [PDF]

open access: yes, 2003
Cadmium (Cd) is a well-known nephrotoxic environmental contaminant but there are indications that the developing nervous system might be even more sensitive to Cd than the kidneys in adults.
Eklund, Gunilla
core  

Providing a Placental Transfusion in Newborns Who Need Resuscitation

open access: yesFrontiers in Pediatrics, 2017
Over the past decade, there have been several studies and reviews on the importance of providing a placental transfusion to the newborn. Allowing a placental transfusion to occur by delaying the clamping of the umbilical cord is an extremely effective ...
A. Katheria   +3 more
semanticscholar   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

EPSTEIN - BARR VIRAL INFECTION: MODERN SITUATION AND CLINICAL-EPIDEMIOLOGICAL FEATURES AMONG FERTILE WOMEN AND NEWBORNS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. The investigate the current manifestations of the symptomatic and inapparent epidemic process of Epstein-Barr infection, as well as identification of its features in women of childbearing age and newborns. Materials and methods.
A. A. Asratyan   +7 more
doaj   +1 more source

Artificial Wombs, Birth, and "Birth": A Response to Romanis [PDF]

open access: yes, 2019
Recently, I argued that human subjects in artificial wombs (AWs) “share the same moral status as newborns” and so, deserve the same treatment and protections as newborns.
Colgrove, Nicholas
core   +1 more source

Screening for seemingly healthy newborns with congenital cytomegalovirus infection by quantitative real-time polymerase chain reaction using newborn urine: an observational study

open access: yesBMJ Open, 2017
Objective Approximately 8–10% of newborns with asymptomatic congenital cytomegalovirus (cCMV) infection develop sensorineural hearing loss (SNHL). However, the relationship between CMV load, SNHL and central nervous system (CNS) damage in cCMV infection ...
A. Yamaguchi   +14 more
semanticscholar   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

The foster caregiving relationship with newborns who have feeding difficulties : a thesis presented in partial fulfilment of the requirements for the Master of Arts endorsed in Psychology at Massey University, Albany, New Zealand [PDF]

open access: yes, 2018
The purpose of this study was to expand on foster care and attachment literature by investigating how the relationship is impacted between a foster caregiver and newborn who experiences feeding difficulties.
Hann, Nari
core  

Infant cortex responds to other humans from shortly after birth [PDF]

open access: yes, 2013
A significant feature of the adult human brain is its ability to selectively process information about conspecifics. Much debate has centred on whether this specialization is primarily a result of phylogenetic adaptation, or whether the brain acquires ...
D Maurer   +29 more
core   +1 more source

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