Results 11 to 20 of about 568,124 (227)

Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells

open access: yesiScience, 2021
Summary A number of new cell death processes have been discovered in recent years, including ferroptosis, which is characterized by the accumulation of lipid peroxidation products derived from iron metabolism. The evidence suggests that ferroptosis has a
Xianjin Kan   +9 more
semanticscholar   +1 more source

A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses

open access: yesNature Communications, 2021
Rapid development of COVID-19 vaccines has helped mitigating SARS-CoV-2 spread, but more equitable allocation of vaccines is necessary to limit the global impact of the COVID-19 pandemic and the emergence of additional variants of concern.
Weina Sun   +24 more
semanticscholar   +1 more source

Newcastle disease virus pathotypes [PDF]

open access: yesAvian Pathology, 1974
The clinical signs, mortality and postmortem findings following infection of six-week-old chicks with nine strains of Newcastle disease virus were studied. Although strains could be divided into four pathotypes the divisions were not clear-cut. The most prominent feature of disease following infection by two isolates from the post-1970 USA epidemic, a ...
D J, Alexander, W H, Allan
openaire   +2 more sources

Thermostability and Immunogenicity of Genotype II Avian Orthoavulavirus (AOaV-1) Isolates from Duck (Anas platyrhynchos) and Parrot (Eclectusroratus)

open access: yesViruses, 2022
Newcastle disease (ND) is a highly contagious viral disease of poultry causing significant economic losses worldwide. Vaccination is considered the most reliable approach to curb the economic menace that is ND, but the thermolabile nature of Newcastle ...
Sangeeta Das   +13 more
doaj   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

Spatial Distribution and Seroprevalence of Newcastle Disease in Kaduna State, Nigeria

open access: yesFolia Veterinaria, 2021
Newcastle disease is one of the greatest constraints to the development of poultry production in Nigeria. In this study, the spatial distribution of Newcastle disease antibodies was determined using the Geographic Information System. A total of 400 serum
Adanu W. A.   +5 more
doaj   +1 more source

Seroprevalence Investigation of Newcastle Disease in Rural Poultries of the Northern Provinces (Golestan, Gilan, and Mazandaran) of Iran [PDF]

open access: yesArchives of Razi Institute, 2019
Rural poultry farming is common in the Northern provinces. Similar to commercial poultry, rural poultry is susceptible to most infectious diseases. In addition, by increasing the density of poultry farming, the probability of disease incidences has been ...
A. Alemian   +3 more
doaj   +1 more source

Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020

open access: yesEmerging Microbes and Infections, 2021
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected ...
Nicola S. Lewis   +21 more
doaj   +1 more source

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate

open access: yesEBioMedicine, 2020
Background Due to the lack of protective immunity of humans towards the newly emerged SARS-CoV-2, this virus has caused a massive pandemic across the world resulting in hundreds of thousands of deaths.
Weina Sun   +12 more
semanticscholar   +1 more source

A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 Vaccine

open access: yesVaccines, 2020
A successful severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine must not only be safe and protective, but must also meet the demand on a global scale at a low cost.
Weina Sun   +15 more
semanticscholar   +1 more source

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