Results 91 to 100 of about 1,681,482 (253)
Colonial Williamsburg: Archaeology, Interpretation and Phenomenology
EXARC Journal, 2019 This paper stems from a keynote talk I was invited to give at the Archaeology for the People: Exhibition, Experience and Performance conference, in Kernave, Lithuania, in September of 2018.
Peter Inker
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
EXARC JournalThis paper discussed the history, archaeology and experimental reconstruction of the Tranent-Cockenzie Waggonway. First it outlines the known chronology of the railway; secondly is describes the archaeology of the wooden phases of the waggonway (1722 ...
Anthony Dawson
doaj
Experimental Reconstruction of a Nineteenth Century Lower Limb Prosthetic Peg Leg – The Box Leg
EXARC Journal, 2018 Scientific attempts to understand early prosthesis manufacturing techniques are rare. The academic research of artificial limbs has been limited to the historical analysis of documentary sources.
Charlotte Waller-Cotterhill
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Interview: Richard Rees, a professional furrier with over 30 years of experience
EXARC JournalWe are talking to Richard Rees, a professional furrier with over 30 years of experience in the profession. He has undertaken an unprecedented project—creating the fifth Qingailisaq parka. The parka is famous for being so difficult to make.
J. Kateřina Dvořáková
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
EXARC Journal, 2012 This interview with Dr. Errett Callahan began in the fall of 2010 during an 8-hour car ride from his home, Cliffside, in Lynchburg, Virginia to Gastonia, North Carolina where we both attended the first annual Reconstructive and Experimental Archaeology ...
Bill Schindler
doaj