Results 101 to 110 of about 1,681,482 (253)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A Personal Experience in Communicating History: Tales From the River Trent
Saturday 1 September dawns gloriously, and is unseasonably sunny. Our fingers are crossed that this is the Indian Summer we'd been praying for all August since we intend to do a lot of walking in the next three weeks.
Sophia Collins
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
‘Re-rolling’ a Mummy: an Experimental Spectacle at Manchester Museum
Ancient Egyptian animal mummies and votive statuettes were often wrapped in linen, concealing the contents and conferring sanctity to the remains. Mummy autopsies were commonplace in 19th century Europe, when ancient mummified bodies were unwrapped to ...
Lidija McKnight
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Itinerant Artist: Portraiting Early America Using Scissors, Soot and Beer
Hundreds of thousands of profile portraits known as silhouettes were created in the new United States in the first decade of 1800 alone. Since the 1990s, museum conservators have wondered how to best care for the materials of these objects in their ...
Lauren Muney
doaj
Hunting with Cane: Traditional Cherokee Blowguns and Darts
The Cherokee Indians were a large Southeastern tribe who occupied land in North Carolina, South Carolina, Georgia, Alabama, Tennessee and Virginia. During the Historic Period, the Cherokee were one of the Five Civilized Tribes and even had their own ...
Doug Meyer
doaj
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Cochineal in the Classroom: Engagement Success with an Ancient Colourant
Cochineal, small insects that feed on nopal (prickly pear) cactus leaves, produce a naturally vibrant red colourant and have been used from ancient times for purposes such as dyeing, painting, and cosmetic applications.
Cara Tremain
doaj
In the framework of the European Research Area for Agricultural Research for Development (ERA-ARD) project, a survey of innovative approaches in capacity development (CD) was undertaken. All Consortium members were asked to describe innovative approaches
Giger, Markus, Kaufmann, Manfred
core

