Results 81 to 90 of about 1,681,482 (253)

Dopaminergic medication enhances subjective enjoyment and improves interactive performance during dyadic motor interactions in patients with Parkinson’s Disease

, 2021
Dopaminergic medication enhances subjective enjoyment and improves interactive performance during dyadic motor interactions in patients with Parkinson’s ...
Vanessa Era
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Newer combination treatments for breast cancer coexisting with acute myeloid leukemia in the novel regimens era: A case report and literature review

Oncology Letters
The occurrence of acute myeloid leukemia (AML) with a simultaneous diagnosis of breast cancer (BC) is rarely reported in the literature. The present study reports the case of a 50-year-old female patient diagnosed with AML coexisting with metastatic BC.
Xing, Lina, Tian, Tian, Li, Yang, Zhang, Jingnan, Guo, Xiaonan, Qiao, Shukai   +5 more
openaire   +2 more sources

Conference Review: Reconstructive and Experimental Archaeology Conference REARC 2012

EXARC Journal, 2013
The third annual Reconstructive and Experimental Archaeology (REARC Conference was hosted by the Schiele Museum of Natural History at Gastonia North Carolina, USA, 19-21 October 2012.
Darrell Markewitz
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

People Want Quality and They are Willing to Pay for it

EXARC Journal, 2013
The international and European notion of cultural and creative industries has not shown much appreciation of the potential of the cultural sector, especially the heritage sector.
Henrik Zipsane
doaj  

Victoria erupts: The Newer Volcanics Province of south-eastern Australia

, 2014
The Newer Volcanics Province of south-eastern Australia is often overlooked, though it comprises a multitude of volcanic features worthy of exploration.
Keays, R., Nicholls, I., Hayman, P., Boyce, J.   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

An Ethnoarchaeological Discussion of the Impact of Religion on Architecture in a Remote Iranian Village

EXARC Journal
In the years 2014 to 2015, an Ethnoarchaeological study of the architecture of Makhunik village (Doreh Rural District, in the Central District of Sarbisheh County, South Khorasan Province, Iran) was done (Rahimkhani 2015).
Tahere Rahimkhani
doaj