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Sequencing technologies — the next generation [PDF]

open access: bronzeNature Reviews Genetics, 2009
Demand has never been greater for revolutionary technologies that deliver fast, inexpensive and accurate genome information. This challenge has catalysed the development of next-generation sequencing (NGS) technologies. The inexpensive production of large volumes of sequence data is the primary advantage over conventional methods.
Stephen Turner
exaly   +5 more sources

Next generation sequencing technologies for next generation plant breeding [PDF]

open access: yesFrontiers in Plant Science, 2014
As a term, “next generation plant breeding” is increasingly becoming popular in crop breeding programmes, conferences, scientific fora and social media (Schnable, 2013). Being a frontier area of crop science and business, it is gaining considerable interest among scientific community and policymakers and funds flow from entrepreneurs and research ...
SOHAM eRAY, PRATIK eSATYA
doaj   +6 more sources

Next generation sequencing

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021
Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
doaj   +5 more sources

Next generation sequencing

open access: yesIndian Journal of Medical and Paediatric Oncology, 2020
Guruprasad Bhat, Amit Kumar Jain
doaj   +5 more sources

Next generation sequencing in cytology [PDF]

open access: yesCytopathology, 2021
AbstractThe application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in ...
Pisapia, Pasquale   +11 more
openaire   +3 more sources

Demystifying the Discussion of Sequencing Panel Size in Oncology Genetic Testing

open access: yesEuropean Medical Journal, 2022
Clinical laboratories worldwide are implementing next-generation sequencing (NGS) to identify cancer genomic variants and ultimately improve patient outcomes. The ability to massively sequence the entire genome or exome of tumour cells has been critical
Cecília Durães   +3 more
doaj   +1 more source

Metagenomic Analysis of Respiratory RNA Virome of Children with and without Severe Acute Respiratory Infection from the Free State, South Africa during COVID-19 Pandemic Reveals Higher Diversity and Abundance in Summer Compared with Winter Period

open access: yesViruses, 2022
Viral respiratory infections contribute to significant morbidity and mortality in children. Currently, there are limited reports on the composition and abundance of the normal commensal respiratory virome in comparison to those in severe acute ...
Ayodeji E. Ogunbayo   +5 more
doaj   +1 more source

Next-Generation Sequencing [PDF]

open access: yesJournal of Biomedicine and Biotechnology, 2010
It has been widely appreciated that the genome sequence is shaping the future biomedical research. The genome sequence provides a general framework for assembling fragmentary DNA information into landscape of biological structure and function [1]. The rapid advances in DNA sequencing technology are revolutionizing biomedical research.
Momiao Xiong   +3 more
openaire   +2 more sources

Next-generation sequencing in dermatology

open access: yesFrontiers in Medicine, 2023
Over the past decade, Next-Generation Sequencing (NGS) has advanced our understanding, diagnosis, and management of several areas within dermatology. NGS has emerged as a powerful tool for diagnosing genetic diseases of the skin, improving upon traditional PCR-based techniques limited by significant genetic heterogeneity associated with these disorders.
Andrew D. King   +5 more
openaire   +3 more sources

In silico prediction of the enzymes involved in the degradation of the herbicide molinate by Gulosibacter molinativorax ON4T

open access: yesScientific Reports, 2022
Gulosibacter molinativorax ON4T is the only known organism to produce molinate hydrolase (MolA), which catalyses the breakdown of the thiocarbamate herbicide into azepane-1-carboxylic acid (ACA) and ethanethiol.
A. R. Lopes   +11 more
doaj   +1 more source

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