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Sequencing technologies — the next generation [PDF]
Demand has never been greater for revolutionary technologies that deliver fast, inexpensive and accurate genome information. This challenge has catalysed the development of next-generation sequencing (NGS) technologies. The inexpensive production of large volumes of sequence data is the primary advantage over conventional methods.
Stephen Turner
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Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
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Next-generation sequencing in dermatology
Over the past decade, Next-Generation Sequencing (NGS) has advanced our understanding, diagnosis, and management of several areas within dermatology.
Andrew D. King+5 more
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The chemistry of next-generation sequencing
The first large genome fully sequenced by next-generation sequencing (NGS) was that of a bacteriophage using sequencing by synthesis (SBS) as a paradigm. SBS in NGS is underpinned by 'reversible-terminator chemistry'. To grow from proof of concept to being both affordable and practical, SBS needed to overcome a series of challenges, each of which ...
Raphaël Rodriguez, Yamuna Krishnan
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Next generation sequencing technologies for next generation plant breeding [PDF]
As a term, “next generation plant breeding” is increasingly becoming popular in crop breeding programmes, conferences, scientific fora and social media (Schnable, 2013). Being a frontier area of crop science and business, it is gaining considerable interest among scientific community and policymakers and funds flow from entrepreneurs and research ...
SOHAM eRAY, PRATIK eSATYA
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Guruprasad Bhat, Amit Kumar Jain
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Next generation sequencing in cytology [PDF]
AbstractThe application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in ...
Pasquale Pisapia+11 more
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Demystifying the Discussion of Sequencing Panel Size in Oncology Genetic Testing
Clinical laboratories worldwide are implementing next-generation sequencing (NGS) to identify cancer genomic variants and ultimately improve patient outcomes. The ability to massively sequence the entire genome or exome of tumour cells has been critical
Cecília Durães+3 more
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Viral respiratory infections contribute to significant morbidity and mortality in children. Currently, there are limited reports on the composition and abundance of the normal commensal respiratory virome in comparison to those in severe acute ...
Ayodeji E. Ogunbayo+5 more
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Next-Generation Sequencing [PDF]
It has been widely appreciated that the genome sequence is shaping the future biomedical research. The genome sequence provides a general framework for assembling fragmentary DNA information into landscape of biological structure and function [1]. The rapid advances in DNA sequencing technology are revolutionizing biomedical research.
Momiao Xiong+3 more
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