Results 261 to 270 of about 519,004 (292)
Some of the next articles are maybe not open access.
Revue medicale de Bruxelles, 2018
Fine needle aspiration is the gold standard method to differentiate benign thyroid nodules from malignant. However, for 15 to 30% of the cases the cytological diagnosis is indeterminate, leading to surgery. Integration of new molecular markers is opening new perspectives in order to increase the diagnostic precision of thyroid nodules with an ...
M, Le Mercier +6 more
+5 more sources
Fine needle aspiration is the gold standard method to differentiate benign thyroid nodules from malignant. However, for 15 to 30% of the cases the cytological diagnosis is indeterminate, leading to surgery. Integration of new molecular markers is opening new perspectives in order to increase the diagnostic precision of thyroid nodules with an ...
M, Le Mercier +6 more
+5 more sources
Next-generation DNA sequencing
Nature Biotechnology, 2008DNA sequence represents a single format onto which a broad range of biological phenomena can be projected for high-throughput data collection. Over the past three years, massively parallel DNA sequencing platforms have become widely available, reducing the cost of DNA sequencing by over two orders of magnitude, and democratizing the field by putting ...
Jay, Shendure, Hanlee, Ji
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Next-Generation Sequencing Platforms
Annual Review of Analytical Chemistry, 2013Automated DNA sequencing instruments embody an elegant interplay among chemistry, engineering, software, and molecular biology and have built upon Sanger's founding discovery of dideoxynucleotide sequencing to perform once-unfathomable tasks. Combined with innovative physical mapping approaches that helped to establish long-range relationships between
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Next generation sequencing technologies
Drug Discovery Today: Technologies, 2005From the investigation of disease-associated loci in humans, to monitoring the changing genomes of pathogenic viruses and bacteria, sequencing is a powerful and versatile tool. A new generation of sequencing technologies will increase the speed and lower the cost of sequencing, and promises to expand the utility of sequencing in drug discovery and ...
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[Next Generation Sequencing and ADPKD].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2015Autosomal Dominant Polycistic Kidney Disease (ADPKD) is the most common inherited genetic disorder in the word, caused by mutations in PKD1 gene in 85% of cases and PKD 2 gene in the remaining 15%. Although diagnosis is usually based on ultrasound, MRI and CT scans, in some cases genetic testing is necessary, for example, in patients with atypical ...
Restivo, Arianna +6 more
openaire +4 more sources
2017
This chapter summarizes the frequency and role of point mutations and small insertions or deletions (indels) in primary prostate cancer (PCa). Compared to other malignancies, PCa is rather characterized by chromosomal aberrations than by gene mutations.
Anne Offermann, Sven Perner
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This chapter summarizes the frequency and role of point mutations and small insertions or deletions (indels) in primary prostate cancer (PCa). Compared to other malignancies, PCa is rather characterized by chromosomal aberrations than by gene mutations.
Anne Offermann, Sven Perner
openaire +1 more source
Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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