Results 161 to 170 of about 783,867 (386)
NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction
Cells, 2019 Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation, and aging. Mechanical stress along with synovial inflammation promotes the degradation of the extracellular matrix in the cartilage, leading to the breakdown of ...
Moon-Chang Choi +4 more
semanticscholar +1 more source
Immunosuppressant FK506 Activates NF-κB through the Proteasome-mediated Degradation of IκBα [PDF]
, 1999 Yong-kang Zhang +7 more
openalex +1 more source
Imine Crosslinked, Injectable, and Self‐Healing Fucoidan Hydrogel with Immunomodulatory Properties
Advanced Healthcare Materials, EarlyView.This study develops an injectable fucoidan‐based hydrogel with tunable properties for tissue engineering. By oxidizing fucoidan (OFu) to introduce aldehydes, imine crosslinks are formed with amine‐containing polymers, enabling self‐healing, injectability, and long‐term stability (≥28 days). The OFu‐gelatin hydrogel demonstrated biocompatibility, immune‐
Asma Talib Qureshi +3 more
wiley +1 more source
Mechanisms of NF-κB p65 and strategies for therapeutic manipulation
Journal of Inflammation Research, 2018 The transcription factor NF-κB is a critical regulator of immune and inflammatory responses. In mammals, the NF-κB/Rel family comprises five members: p50, p52, p65 (Rel-A), c-Rel, and Rel-B proteins, which form homo- or heterodimers and remain as an ...
Sivagami Giridharan, M. Srinivasan
semanticscholar +1 more source
Epstein-Barr Virus Binding to CD21 Activates the Initial Viral Promoter via NF-κB Induction [PDF]
, 1997 Naoyuki Sugano +3 more
openalex +1 more source
Advanced Materials, EarlyView.This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang +3 more
wiley +1 more source
Cell Reports, 2023 Summary: The nuclear factor κB (NF-κB) pathway plays essential roles in innate and adaptive immunity, but little is known how NF-κB signaling is compartmentalized and spatiotemporally activated in the cytoplasm.
Xia Fei +21 more
doaj
Ultra‐Fine 3D Bioprinting of Dynamic Hyaluronic Acid Hydrogel for in Vitro Modeling
Advanced Materials, EarlyView.3D bioprinting merges tissue engineering and additive manufacturing to create biological structures. A bioink is developed by modifying hyaluronic acid, a natural extracellular matrix polymer, with cysteine. Potassium iodide is later added to tune gelation kinetics, enabling fine printing with a 32G needle.
Shima Tavakoli +3 more
wiley +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source